CYANTRANILIPROLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H14BrClN6O2
Molecular Weight	473.71
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(=O)C1=C(NC(=O)C2=CC(Br)=NN2C3=NC=CC=C3Cl)C(C)=CC(=C1)C#N

InChI

InChIKey=DVBUIBGJRQBEDP-UHFFFAOYSA-N

InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)

HIDE SMILES / InChI

Molecular Formula	C19H14BrClN6O2
Molecular Weight	473.71
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.mda.state.mn.us/chemicals/pesticides/regs/~/media/Files/chemicals/reviews/nair-cyantraniliprole.pdf

Cyantraniliprole (HGW-86) is an insecticide of the ryanoid class, is a systemic insecticide that works by impairing the regulation of muscle contractions causing paralysis and eventual death in insects. It’s a ryanodine receptor (RyR) modulator which kills insects though unregulated activation of RyR. Cyantraniliprole is approved for use in the United States, Canada, China, and India; it is highly toxic to bees, which resulted in registration of its use as a pesticide being delayed in the USA.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
ryanodine receptor of insects 1 Target ID: ryanodine receptor of insects Sources: http://www.mda.state.mn.us/chemicals/pesticides/regs/~/media/Files/chemicals/reviews/nair-cyantraniliprole.pdf	Modulator 846

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Effects of three diamides (chlorantraniliprole, cyantraniliprole and flubendiamide) on life history, embryonic development and oxidative stress biomarkers of Daphnia magna.	2017-02	27870931
Susceptibility of Helicoverpa armigera (Lepidoptera: Noctuidae) to Cyantraniliprole Determined From Topical and Ingestion Bioassays.	2016-02-25	26921229
Effects of Sublethal Concentrations of Cyantraniliprole on the Development, Fecundity and Nutritional Physiology of the Black Cutworm Agrotis ipsilon (Lepidoptera: Noctuidae).	2016	27249654
Evaluation of Cyantraniliprole and Other Commercial Fly Baits under Laboratory and Field Conditions.	2015-11-23	26610575

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:49:10 GMT 2025` Edited by `admin` on `Mon Mar 31 22:49:10 GMT 2025`
Record UNII	LO6K6H48FD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYAZYPYR

Preferred Name

English

CYANTRANILIPROLE

Common Name

English

CYANTRANILIPROLE [MI]

Common Name

English

SYN-545377

Code

English

CYANTRANILIPROLE [ISO]

Common Name

English

DPX-HGW 86

Code

English

BENEVIA

Common Name

English

3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-N-(4-CYANO-2-METHYL-6-(N-METHYLCARBAMOYL)PHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE

Systematic Name

English

EXIREL (INSECTICIDE)

Common Name

English

1H-PYRAZOLE-5-CARBOXAMIDE, 3-BROMO-1-(3-CHLORO-2-PYRIDINYL)-N-(4-CYANO-2-METHYL-6-((METHYLAMINO)CARBONYL)PHENYL)-

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

90098