U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C19H14BrClN6O2
Molecular Weight 473.71
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYANTRANILIPROLE

SMILES

CNC(=O)C1=C(NC(=O)C2=CC(Br)=NN2C3=NC=CC=C3Cl)C(C)=CC(=C1)C#N

InChI

InChIKey=DVBUIBGJRQBEDP-UHFFFAOYSA-N
InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)

HIDE SMILES / InChI

Molecular Formula C19H14BrClN6O2
Molecular Weight 473.71
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Cyantraniliprole (HGW-86) is an insecticide of the ryanoid class, is a systemic insecticide that works by impairing the regulation of muscle contractions causing paralysis and eventual death in insects. It’s a ryanodine receptor (RyR) modulator which kills insects though unregulated activation of RyR. Cyantraniliprole is approved for use in the United States, Canada, China, and India; it is highly toxic to bees, which resulted in registration of its use as a pesticide being delayed in the USA.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
LO6K6H48FD
Record Status Validated (UNII)
Record Version