U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:08:08 GMT 2023
Edited
by admin
on Sat Dec 16 12:08:08 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
LLJ6UPO71A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NITRIC OXIDE SYNTHASE, INDUCIBLE
Common Name English
PEPTIDYL-CYSTEINE S-NITROSYLASE NOS2
Common Name English
NOS type II
Common Name English
HEPATOCYTE NOS
Common Name English
NOS2A
Common Name English
INDUCIBLE NO SYNTHASE
Common Name English
Code System Code Type Description
FDA UNII
LLJ6UPO71A
Created by admin on Sat Dec 16 12:08:08 GMT 2023 , Edited by admin on Sat Dec 16 12:08:08 GMT 2023
PRIMARY
UNIPROT
P35228
Created by admin on Sat Dec 16 12:08:08 GMT 2023 , Edited by admin on Sat Dec 16 12:08:08 GMT 2023
PRIMARY
Related Record Type Details
INDUCER -> TARGET
WEAK INHIBITOR->TARGET
INHIBITOR OF EXPRESSION->TARGET
INHIBITOR -> TARGET
Slow, tight binding inhibitor of human inducible nitric- oxide synthase (iNOS). Inhibited enzyme did not recover activity after 2 h. Thus, 1400W was either an irreversible inhibitor or an extremely slowly reversible inhibitor of human iNOS with a Kd value ≤ 7 nM.
TIME-DEPENDENT INHIBITION
Ki
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL