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Details

Stereochemistry ACHIRAL
Molecular Formula C28H24FN3O6
Molecular Weight 517.5061
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-(4-((6,7-DIMETHOXY-1-OXIDO-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-1,1-CYCLOPROPANEDICARBOXAMIDE

SMILES

COc1cc2c(cc1OC)n(=O)ccc2Oc3ccc(cc3)NC(=O)C4(CC4)C(=O)Nc5ccc(cc5)F

InChI

InChIKey=FKJJTKYQXXLFPS-UHFFFAOYSA-N
InChI=1S/C28H24FN3O6/c1-36-24-15-21-22(16-25(24)37-2)32(35)14-11-23(21)38-20-9-7-19(8-10-20)31-27(34)28(12-13-28)26(33)30-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,30,33)(H,31,34)

HIDE SMILES / InChI

Molecular Formula C28H26FN3O6
Molecular Weight 519.522
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Fri Jun 25 21:41:07 UTC 2021
Edited
by admin
on Fri Jun 25 21:41:07 UTC 2021
Record UNII
LKX6L2LD4X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-(4-((6,7-DIMETHOXY-1-OXIDO-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-1,1-CYCLOPROPANEDICARBOXAMIDE
Systematic Name English
1,1-CYCLOPROPANEDICARBOXAMIDE, N-(4-((6,7-DIMETHOXY-1-OXIDO-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-
Systematic Name English
CABOZANTINIB METABOLITE M19
Common Name English
EXEL-5162
Common Name English
Code System Code Type Description
CAS
1621681-63-7
Created by admin on Fri Jun 25 21:41:07 UTC 2021 , Edited by admin on Fri Jun 25 21:41:07 UTC 2021
PRIMARY
PUBCHEM
78325042
Created by admin on Fri Jun 25 21:41:07 UTC 2021 , Edited by admin on Fri Jun 25 21:41:07 UTC 2021
PRIMARY
FDA UNII
LKX6L2LD4X
Created by admin on Fri Jun 25 21:41:07 UTC 2021 , Edited by admin on Fri Jun 25 21:41:07 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
IC50
Related Record Type Details
PARENT -> METABOLITE
MAJOR
PLASMA
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Tmax PHARMACOKINETIC