EVOLOCUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 06:59:51 UTC 2023` Edited by `admin` on `Sat Dec 16 06:59:51 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	LKC0U3A8NJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EVOLOCUMAB

Official Name

English

EVOLOCUMAB [JAN]

Common Name

English

REPATHA

Brand Name

English

EVOLOCUMAB [PURPLE BOOK CDER]

Common Name

English

EVOLOCUMAB (GENETICAL RECOMBINATION)

Official Name

English

IMMUNOGLOBULIN G2-LAMBDA, ANTI-(HOMO SAPIENS PCSK9 (PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9)), HOMO SAPIENS MONOCLONAL ANTIBODY

Common Name

English

evolocumab [INN]

Common Name

English

Evolocumab [WHO-DD]

Common Name

English

AMG-145

Code

English

EVOLOCUMAB [USAN]

Common Name

English

EVOLOCUMAB [MI]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000191731

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

FDA ORPHAN DRUG

404113

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

WHO-ATC

C10AX13

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

Code System Code Type Description

DRUG BANK

DB09303

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

EVMPD

SUB128552

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

USAN

AB-13

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

CAS

1256937-27-5

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

HSDB

8307

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

FDA UNII

LKC0U3A8NJ

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

JAPANESE REVIEW

REPATHA

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

APPROVED JANUARY 2016

LACTMED

Evolocumab

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

ChEMBL

CHEMBL2364655

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

MERCK INDEX

m11845

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

IUPHAR

7343

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

RXCUI

1665684

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

RxNorm

NDF-RT

N0000191730

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

PCSK9 Inhibitors [MoA]

NCI_THESAURUS

C174672

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

DRUG CENTRAL

5000

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

SMS_ID

100000154364

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

DAILYMED

LKC0U3A8NJ

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

WIKIPEDIA

EVOLOCUMAB

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

CAS

1420806-15-0

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

SUPERSEDED

INN

9643

Created by admin on Sat Dec 16 06:59:51 UTC 2023 , Edited by admin on Sat Dec 16 06:59:51 UTC 2023

PRIMARY

From	To
1_22	1_96
1_142	1_198
1_255	1_315
1_361	1_419
2_22	2_96
2_142	2_198
2_255	2_315
2_361	2_419
3_22	3_90
3_137	3_196
4_22	4_90
4_137	4_196
1_129	3_214
2_129	4_214
1_217	2_217
1_218	2_218
1_221	2_221
1_224	2_224

Glycosylation Link Type	Site
N	1_291
N	2_291

Related Record Type Details


					LGW95S5DG1

PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9

TARGET -> INHIBITOR

Related Record Type Details


					LKC0U3A8NJ

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL