U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2015
472
Substance Class Protein
Created
by admin
on Mon Mar 31 21:39:54 GMT 2025
Edited
by admin
on Mon Mar 31 21:39:54 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
LKC0U3A8NJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EVOLOCUMAB (GENETICAL RECOMBINATION)
JAN  
Preferred Name English
EVOLOCUMAB
DASH   INN   USAN   WHO-DD  
INN   USAN  
Official Name English
EVOLOCUMAB [JAN]
Common Name English
REPATHA
Brand Name English
EVOLOCUMAB [PURPLE BOOK CDER]
Common Name English
IMMUNOGLOBULIN G2-LAMBDA, ANTI-(HOMO SAPIENS PCSK9 (PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9)), HOMO SAPIENS MONOCLONAL ANTIBODY
Common Name English
evolocumab [INN]
Common Name English
Evolocumab [WHO-DD]
Common Name English
AMG-145
Code English
EVOLOCUMAB [USAN]
Common Name English
EVOLOCUMAB [MI]
Common Name English
Classification Tree Code System Code
NDF-RT N0000191731
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
FDA ORPHAN DRUG 404113
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
WHO-ATC C10AX13
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
Code System Code Type Description
DRUG BANK
DB09303
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
EVMPD
SUB128552
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
USAN
AB-13
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
CAS
1256937-27-5
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
HSDB
8307
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
FDA UNII
LKC0U3A8NJ
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
JAPANESE REVIEW
REPATHA
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY APPROVED JANUARY 2016
LACTMED
Evolocumab
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
ChEMBL
CHEMBL2364655
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
MERCK INDEX
m11845
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
IUPHAR
7343
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
RXCUI
1665684
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY RxNorm
NDF-RT
N0000191730
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY PCSK9 Inhibitors [MoA]
NCI_THESAURUS
C174672
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
DRUG CENTRAL
5000
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
SMS_ID
100000154364
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
DAILYMED
LKC0U3A8NJ
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
WIKIPEDIA
EVOLOCUMAB
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
CAS
1420806-15-0
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
SUPERSEDED
INN
9643
Created by admin on Mon Mar 31 21:39:54 GMT 2025 , Edited by admin on Mon Mar 31 21:39:54 GMT 2025
PRIMARY
From To
1_22 1_96
1_142 1_198
1_255 1_315
1_361 1_419
2_22 2_96
2_142 2_198
2_255 2_315
2_361 2_419
3_22 3_90
3_137 3_196
4_22 4_90
4_137 4_196
1_129 3_214
2_129 4_214
1_217 2_217
1_218 2_218
1_221 2_221
1_224 2_224
Glycosylation Link Type Site
N 1_291
N 2_291
Related Record Type Details
PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
TARGET -> INHIBITOR
Related Record Type Details
EVOLOCUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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