NYASOL

OC1=CC=C(\C=C/[C@@H](C=C)C2=CC=C(O)C=C2)C=C1

InChIKey=VEAUNWQYYMXIRB-JHAQOBCDSA-N

InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2/b6-3-/t14-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	1
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
Plasmodium falciparum 75 Target ID: CHEMBL364 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16392829	Inhibitor 8504
Respiratory syncytial virus 4 Target ID: CHEMBL612679 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17886842	Positive Allosteric Modulator 186		0.85 µM [IC50]

PubMed

Title	Date	PubMed
Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.	2006-01-12	16392829

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:21:42 GMT 2025` Edited by `admin` on `Wed Apr 02 11:21:42 GMT 2025`
Record UNII	LK6CH9D7UR
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NYASOL

Common Name

English

(-)-NYASOL

Preferred Name

English

PHENOL, 4,4-((1Z,3R)-3-ETHENYL-1-PROPENE-1,3-DIYL)BIS-

Systematic Name

English

CIS-HINOKIRESINOL

Common Name

English

Z-(-)HINOKIRESINOL

Common Name

English

PHENOL, 4,4-(3-ETHENYL-1-PROPENE-1,3-DIYL)BIS-, (R-(Z))-

Systematic Name

English

4,4-((1Z,3R)-3-ETHENYL-1-PROPENE-1,3-DIYL)BIS(PHENOL)

Systematic Name

English

Code System Code Type Description

PUBCHEM

6915833