CX-039300

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 19:52:56 UTC 2023` Edited by `admin` on `Sat Dec 16 19:52:56 UTC 2023`
Nucleic Acid Type	mRNA VACCINE
Nucleic Acid Subtype	VIRAL ENVELOPE PROTEIN
Sequence Origin	VIRAL
Sequence Type	COMPLETE
Record UNII	LG5UQ83MXK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CX-039300

Code

English

RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 pre-fusion spike glycoprotein [983-proline,984-proline] DS.1 variant plus 5′- and 3′-untranslated

Common Name

English

Code System Code Type Description

CAS

2918977-07-6

Created by admin on Sat Dec 16 19:52:57 UTC 2023 , Edited by admin on Sat Dec 16 19:52:57 UTC 2023

PRIMARY

FDA UNII

LG5UQ83MXK

Created by admin on Sat Dec 16 19:52:57 UTC 2023 , Edited by admin on Sat Dec 16 19:52:57 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_4102	4102 / 4102

Linkage	Site Range	Site Count
Phosphate	1_2-1_4102	4101 / 4101

Related Record Type Details


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->VACCINE ANTIGEN

Amount:

Related Record Type Details


					LG5UQ83MXK

CX-039300

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]				5'-GUANOSINE-M-RNA-CAP-1-3'-PHOSPHATE	T0HQY09X7B
NUCLEOSIDE_SUBSTITUTION			U		N1-METHYLPSEUDOURIDINE	09RAD4M6WF