Safimestomig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:13:15 GMT 2025` Edited by `admin` on `Wed Apr 02 11:13:15 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	LFQ9PP64F2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

6MW3211

Preferred Name

English

Safimestomig

Official Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens CD47 (CD47 molecule, integrin associated protein, IAP, MER6, OA3)] and anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)], humanized monoclonal antibo

Common Name

English

Immunoglobulin G4 [232-proline,360-lysine,439-arginine], bispecific, anti-(human CD47 antigen) (human-Mus musculus monoclonal 6MW3211 ?4-chain), (230?228?),(233?225?)-bis(disulfide) with immunoglobulin G4 [227-proline,438-glutamic acid] anti-(human progr

Common Name

English

safimestomig [INN]

Common Name

English

H-gamma4 heavy chain anti-CD47 humanized (1-451) [VH (Homo sapiens IGHV1-3*01 (85.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124)-Homo sapiens IGHG4*01 nG4m(a) CH2 L92, G4v5 h P10, G4v6 CH3 K88, G4v11CH1 Q100, CH2 Y84.3, G4

Common Name

English

Code System Code Type Description

FDA UNII

LFQ9PP64F2