Alextatug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:38:15 GMT 2023` Edited by `admin` on `Sat Dec 16 15:38:15 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	LF64CQ4EC6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Alextatug

Official Name

English

Immunoglobulin G1-lambda7, anti-[Homo sapiens tumor-restricted extracellular ribonucleoprotein (RNP) complex containing PABPC1 (polyadenylate-binding protein cytoplasmic 1, PABP1)bound to poly(A)RNA], Homo sapiens monoclonal antibody

Common Name

English

ATRC-101

Common Name

English

alextatug [INN]

Common Name

English

Immunoglobulin G1 [de-C-terminal lysine], anti-(tumor-associated polyadenylate-binding protein-poly(A) RNA complex) (human monoclonal ATRC-101 γ1-chain), disulfide with human monoclonal ATRC-101 λ-chain, dimer

Common Name

English

Gamma1 heavy chain Homo sapiens (1-469) [VH (Homo sapiens IGHV3-15*02 (95.0%) -(IGHD) -IGHJ6*04 (85.0%), CDR-IMGT [8.10.31] (26-33.51-60.99-129)) (1-140) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (237) (141-238), hinge 1

Common Name

English

Code System Code Type Description

FDA UNII

LF64CQ4EC6

Created by admin on Sat Dec 16 15:38:15 GMT 2023 , Edited by admin on Sat Dec 16 15:38:15 GMT 2023

PRIMARY

INN

12819

Created by admin on Sat Dec 16 15:38:15 GMT 2023 , Edited by admin on Sat Dec 16 15:38:15 GMT 2023

PRIMARY

CAS

2768264-93-1

Created by admin on Sat Dec 16 15:38:15 GMT 2023 , Edited by admin on Sat Dec 16 15:38:15 GMT 2023

PRIMARY

From	To
1_22	1_98
1_103	1_109
1_104	1_117
1_167	1_223
1_249	2_249
1_252	2_252
1_284	1_344
1_390	1_448
2_22	2_98
2_104	2_117
2_167	2_223
2_284	2_344
2_390	2_448
3_22	3_89
3_138	3_197
1_243	3_215
4_22	4_89
4_138	4_197
2_243	4_215
2_103	2_109

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_320
N	2_320

Related Record Type Details


					HPQ7OD5QJI

POLYADENYLATE-BINDING PROTEIN 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					LF64CQ4EC6

Alextatug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL