OPC-28326 ANHYDROUS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H35N3O2.ClH
Molecular Weight	458.036
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC(=O)NC1=C(C)C=C(C=C1C)C(=O)N2CCC(CC2)N(C)CCC3=CC=CC=C3

InChI

InChIKey=ADNUSXMBYGPKTH-UHFFFAOYSA-N

InChI=1S/C26H35N3O2.ClH/c1-5-24(30)27-25-19(2)17-22(18-20(25)3)26(31)29-15-12-23(13-16-29)28(4)14-11-21-9-7-6-8-10-21;/h6-10,17-18,23H,5,11-16H2,1-4H3,(H,27,30);1H

HIDE SMILES / InChI

Molecular Formula	C26H35N3O2
Molecular Weight	421.575
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
OPC-28326, a selective femoral arterial vasodilator, augments ischemia induced angiogenesis.	2007-05	17223008
Efficacy and tolerability of a selective alpha(2C)-adrenergic receptor blocker in recovery from cold-induced vasospasm in scleroderma patients: a single-center, double-blind, placebo-controlled, randomized crossover study.	2004-12	15593189
Effect of oral OPC-28326, a selective femoral arterial vasodilator, on hindlimb subcutaneous tissue temperature in conscious dogs under buprenorphine sedation.	2002-01	11855671
OPC-28326, a selective femoral vasodilator, is an alpha2C-adrenoceptor-selective antagonist.	2001-11	11602678
alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator.	2001-10	11606316
Mechanisms of action of OPC-28326, a selective hindlimb vasodilator.	1999-11	10525078

Substance Class	Chemical Created by `admin` on `Tue Apr 01 21:09:06 GMT 2025` Edited by `admin` on `Tue Apr 01 21:09:06 GMT 2025`
Record UNII	LE5Y6NVZ3S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

4-(N-METHYL-2-PHENYLETHYLAMINO)-1-(3, 5-DIMETHYL-4-PROPIONYLAMINOBENZOYL)PIPERIDINE HYDROCHLORIDE

Preferred Name

English

OPC-28326 ANHYDROUS

Code

English

PROPANAMIDE, N-(2,6-DIMETHYL-4-((4-(METHYL(2-PHENYLETHYL)AMINO)-1-PIPERIDINYL)CARBONYL)PHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID20168338

Created by admin on Tue Apr 01 21:09:06 GMT 2025 , Edited by admin on Tue Apr 01 21:09:06 GMT 2025

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CAS

167621-24-1

Created by admin on Tue Apr 01 21:09:06 GMT 2025 , Edited by admin on Tue Apr 01 21:09:06 GMT 2025

PRIMARY

FDA UNII

LE5Y6NVZ3S

Created by admin on Tue Apr 01 21:09:06 GMT 2025 , Edited by admin on Tue Apr 01 21:09:06 GMT 2025

PRIMARY

PUBCHEM

219019

Created by admin on Tue Apr 01 21:09:06 GMT 2025 , Edited by admin on Tue Apr 01 21:09:06 GMT 2025

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