Claseprubart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:30:47 GMT 2025` Edited by `admin` on `Wed Apr 02 19:30:47 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	LDW8BPL8GB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Immunoglobulin G4 [40-alanine,77-asparagine,100-glutamic acid,101-asparagine,225-proline,232-glutamic acid,249-tyrosine,251-threonine,253-glutamic acid,de-C-terminal lysine], anti-(human/Macaca fascicularis complement C1s) (human monoclonal DNTH103 ?4-ch

Preferred Name

English

Claseprubart

Common Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens C1S (complement C1s)], Homo sapiens monoclonal antibody (H-gamma4 heavy chain Homo sapiens (1-443) [VH (Homo sapiens IGHV3-11*01 (96.9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117)

Common Name

English

claseprubart [INN]

Common Name

English

Code System Code Type Description

INN

13138

Created by admin on Wed Apr 02 19:30:47 GMT 2025 , Edited by admin on Wed Apr 02 19:30:47 GMT 2025

PRIMARY

CAS

2922766-89-8

Created by admin on Wed Apr 02 19:30:47 GMT 2025 , Edited by admin on Wed Apr 02 19:30:47 GMT 2025

PRIMARY

FDA UNII

LDW8BPL8GB

Created by admin on Wed Apr 02 19:30:47 GMT 2025 , Edited by admin on Wed Apr 02 19:30:47 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_131	4_214
2_144	2_200
2_258	2_318
1_131	3_214
2_364	2_422
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_144	1_200
1_223	2_223
1_226	2_226
1_258	1_318
1_364	1_422

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_294
N	2_294

Related Record Type Details


					LDW8BPL8GB

Claseprubart

ACTIVE MOIETY

Comments:

DNTH103 to inhibit the complement CP

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL