Tilrekimig

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:29:36 GMT 2025` Edited by `admin` on `Wed Apr 02 10:29:36 GMT 2025`
Protein Type	TRISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|KAPPA\|LAMDA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	LD48NPB5QS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin, anti-(human/Macaca fascicularis interleukin 13) (human-Mus musculus monoclonal PF-07296735 ?-chain) fusion protein with peptide linker (GGGGS) fusion protein with immunoglobulin G1 [448-glutamic acid,461-alanine,462-alanine,464-alanine,59

Preferred Name

English

Tilrekimig

Official Name

English

tilrekimig [INN]

Common Name

English

TILREKIMIG [USAN]

Common Name

English

PF-07275315

Code

English

Code System Code Type Description

CAS

2981469-90-1

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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USAN

MN-112

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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FDA UNII

LD48NPB5QS

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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INN

13516

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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NCI_THESAURUS

C211783

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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SMS_ID

300000041930

Created by admin on Wed Apr 02 10:29:36 GMT 2025 , Edited by admin on Wed Apr 02 10:29:36 GMT 2025

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From	To
5_136	5_195
5_22	5_87
4_138	4_198
4_23	4_92
3_145	3_201
3_22	3_95
2_372	2_430
2_266	2_326
2_225	5_213
2_149	2_205
2_22	2_96
1_456	2_234
1_453	2_231
1_447	4_218
1_218	3_221
1_594	1_652
1_488	1_548
1_371	1_427
1_245	1_320
1_138	1_198
1_23	1_92

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_524
N	2_302

Related Record Type Details


					LD48NPB5QS

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_674] [2_452]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL