PSEUDOTROPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H15NO
Molecular Weight	141.2108
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1[C@H]2CC[C@@H]1C[C@@H](O)C2

InChI

InChIKey=CYHOMWAPJJPNMW-RNLVFQAGSA-N

InChI=1S/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3/t6-,7+,8-

HIDE SMILES / InChI

Molecular Formula	C8H15NO
Molecular Weight	141.2108
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10387002

Pseudotropine (ψ-tropine, or psi-tropine) is an isomer of tropine. Pseudotropine is formed during NADPH-dependent reduction of the 3-carbonyl group of tropinone to a beta-hydroxyl group. Tropinone reductase-II is an enzyme responsible for this transformation. It is known, that tropinone reductase-II is also a key enzyme in the biosynthetic pathway of tropane alkaloids, which include medicinally important compounds such as hyoscyamine (atropine) and cocaine.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Treatment of Cushing disease: overview and recent findings.	2010-10-21	21063461
The functional divergence of short-chain dehydrogenases involved in tropinone reduction.	2008-05	18221363
Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants.	2006-07-04	16516930
Calystegines in wild and cultivated Erythroxylum species.	2005-06	15907958
Structure-activity relationships among derivatives of dicarboxylic acid esters of tropine.	2002-10	12441175
Neuromuscular pharmacology of TAAC3, a new nondepolarizing muscle relaxant with rapid onset and ultrashort duration of action.	2002-04	11916790
The new neuromuscular blocking agents: do they offer any advantages?	2001-12	11878696
Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.	1999-08-26	10464017

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:56:21 GMT 2025` Edited by `admin` on `Mon Mar 31 22:56:21 GMT 2025`
Record UNII	L9Q7Z9D09L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-43871

Preferred Name

English

PSEUDOTROPINE

Common Name

English

PSEUDOTROPINE [MI]

Common Name

English

PSEUDOTROPANOL

Common Name

English

.PSI.-TROPINE

Common Name

English

8-AZABICYCLO(3.2.1)OCTAN-3-OL, 8-METHYL-, (3-EXO)-

Common Name

English

3-PSEUDOTROPANOL

Common Name

English

3.BETA.-TROPANOL

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

205-226-5