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Approval Year

Unknown
139594
Substance Class
Concept
Record UNII
L93WSG9AAU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NG-641
Code English
NG 641 [WHO-DD]
Common Name English
oncolytic adenoviral vector which expresses a FAP-TAc antibody together with an immune enhancer module (CXCL9/CXCL10/IFNα)
Common Name English
NG641
Code English
NG-641 (AN ONCOLYTIC ADENOVIRAL VECTOR ENCODES FOUR SEPARATE GENES: A FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETING BISPECIFIC T-CELL ACTIVATOR (FAP-TAC) TO ACTIVATE T-CELLS AND DECREASE THE TUMOR ASSOCIATED FIBROBLASTS IN TUMOR STROMA, CHEMOKINES CXCL9
Common Name English
Code System Code Type Description
NCI_THESAURUS
C168790
Created by admin on Sat Dec 16 18:51:36 GMT 2023 , Edited by admin on Sat Dec 16 18:51:36 GMT 2023
PRIMARY
FDA UNII
L93WSG9AAU
Created by admin on Sat Dec 16 18:51:36 GMT 2023 , Edited by admin on Sat Dec 16 18:51:36 GMT 2023
PRIMARY
This is a non-substance concept
Related Record Type Details
PROLYL ENDOPEPTIDASE FAP
TARGET->LIGAND
PRECLINICAL
C-X-C MOTIF CHEMOKINE 10
EXPRESSED PROTEIN->VECTOR
CD3
CD3
TARGET -> ACTIVATOR
PRECLINICAL
INTERFERON ALFA-2B
EXPRESSED PROTEIN->VECTOR
C-X-C MOTIF CHEMOKINE 9
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
NG-641
ACTIVE MOIETY
This is a non-substance concept
NIH
NCATS
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