Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H6O6S |
Molecular Weight | 218.184 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=C(O)C=CC(=C1)S(O)(=O)=O
InChI
InChIKey=YCPXWRQRBFJBPZ-UHFFFAOYSA-N
InChI=1S/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13)
Molecular Formula | C7H6O6S |
Molecular Weight | 218.184 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Sulfosalicylic acid dihydrate is a polyfunctional metal chelating ligand that may be used as a metal scavenger.to form metal coordination complexes. Sulfosalicylic acid forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. Proteins are precipitated upon complexation with 5-Sulfosalicylic acid, allowing the qualitative analysis of the resultant turbidity formed in a sample by these complexes leaving solution. Protein precipitation with 5-Sulfosalicylic acid has also been employed as a preparative measure for removing proteins prior to chromatographic analysis.
Approval Year
PubMed
Title | Date | PubMed |
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Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. | 2001 Jan |
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Determination of selenium sulfide using 1,3-dibromo-5,5-dimethylhydantoin (DBH). Analytical methods of pharmacopeias with DBH in respect to environmental and economical concern Part 11. | 2002 Apr 15 |
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Mutational analysis of the metabolism of 2,6-naphthalenedisulfonate by Pigmentiphaga sp. NDS-2. | 2003 |
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Poly[aquaneodymium(III)-mu5-2-oxido-5-sulfonatobenzoato]. | 2004 Dec |
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Potentiometric membrane sensors based on zirconyl(IV) phthalocyanine for detection of sulfosalicylic acid. | 2004 May 28 |
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Equilibrium studies on chromium(III) complexes of salicylic acid and salicylic acid derivatives in aqueous solution. | 2004 Nov |
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Indirect photometric assay determination of gabapentin in bulk drug and capsules by capillary electrophoresis. | 2004 Nov 15 |
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The role of benzoate secreted by Desulfotomaculum acetoxidans DSM 771 in sulfate uptake. | 2005 |
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Comparison of gene expression signatures of diamide, H2O2 and menadione exposed Aspergillus nidulans cultures--linking genome-wide transcriptional changes to cellular physiology. | 2005 Dec 20 |
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Hydrogen bonding in 1:1 proton-transfer compounds of 5-sulfosalicylic acid with 4-X-substituted anilines (X = F, Cl or Br). | 2005 Feb |
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Separation of aceclofenac and diclofenac in human plasma by free zone capillary electrophoresis using N-methyl-D-glucamine as an effective electrolyte additive. | 2005 Mar |
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Development of a kinetic metabolic model: application to Catharanthus roseus hairy root. | 2006 Apr |
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In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. | 2006 Aug 16 |
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Serial separation of cations and anions by ion chromatography using the peak parking technique and sulfosalicylic acid as the eluent. | 2006 Feb |
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Syntheses, structures, and characterizations of four new lead(II) 5-sulfosalicylate complexes with both chelating and bridging neutral ligands. | 2007 Aug 6 |
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2-Carboxy-quinolinium-2,4,6-trinitro-benzene-sulfonate-quinolinium-2-carboxyl-ate (1/1/1). | 2007 Dec 6 |
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Two salts of 5-sulfosalicylic acid and 3-aminopyridine. | 2007 Nov |
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R2(2)(8) motifs in Aminopyrimidine sulfonate/carboxylate interactions: crystal structures of pyrimethaminium benzenesulfonate monohydrate (2:2:1) and 2-amino-4,6-dimethylpyrimidinium sulfosalicylate dihydrate (4:2:2). | 2007 Nov 13 |
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The toxic function of cesium 5-sulfosalicylate based on the investigation of its trans-erythrocytes membrane behaviors and morphological properties. | 2008 Feb 15 |
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Pyrazine-diium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate. | 2008 Jun 19 |
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1-Hydroxy-ethyl-2-methyl-5-nitro-imidazolium 3-carb-oxy-4-hydroxy-benzene-sulfonate. | 2008 Jun 25 |
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In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. | 2008 Oct 15 |
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Poly[[diaqua(μ(2)-4,4'-dipyridyl sulfide-κN:N')(4,4'-dipyridyl sulfide-κN)(2-hydroxy-5-sulfonatobenzoato-κO)nickel(II)] dihydrate]. | 2008 Sep 20 |
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Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis. | 2009 |
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Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats. | 2009 Jul |
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Proton transfer versus nontransfer in compounds of the diazo-dye precursor 4-(phenyldiazenyl)aniline (aniline yellow) with strong organic acids: the 5-sulfosalicylate and the dichroic benzenesulfonate salts, and the 1:2 adduct with 3,5-dinitrobenzoic acid. | 2009 Oct |
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Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments. | 2009 Oct |
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Aqua-(2-hydr-oxy-5-sulfonatobenzoato-κO)bis-(2-phenyl-1H-1,3,7,8-tetra-aza-cyclo-penta-[l]phenanthrene-κN,N)zinc(II). | 2009 Oct 3 |
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Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke. | 2009 Sep 3 |
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Removal of transition metal ions from aqueous solutions by adsorption onto a novel silica gel matrix composite adsorbent. | 2009 Sep 30 |
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Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury. | 2010 Apr 23 |
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2-Amino-5-chloro-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate. | 2010 Aug 18 |
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Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection. | 2010 Aug 27 |
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2-Amino-5-bromo-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate. | 2010 Aug 28 |
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Acetaminophen induces apoptosis in rat cortical neurons. | 2010 Dec 10 |
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Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass. | 2010 Feb 12 |
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Effect of dietary fats on oxidative-antioxidative status of blood in rats. | 2010 Jul |
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Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage. | 2010 Jul |
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[Hydrogen bis-(1,2,4-triazole)] 1,2,4-triazolium bis-(3-carb-oxy-4-hy-droxy-benzene-sulfonate) 1,2,4-triazole disolvate. | 2010 Jul 17 |
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2-Amino-4-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate monohydrate. | 2010 Jul 24 |
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2-Amino-5-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate. | 2010 Jul 31 |
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Salts of aromatic amines: crystal structures, spectroscopic and non-linear optical properties. | 2010 Nov |
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Identification of protonation state by XPS, solid-state NMR, and DFT: characterization of the nature of a new theophylline complex by experimental and computational methods. | 2010 Nov 11 |
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A simple colorimetric FIA method for the determination of pyrite oxidation rates. | 2010 Oct 15 |
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Polynuclear complexes of macrocyclic oxamide with 5-sulfosalicylate: syntheses, crystal structures and magnetic properties. | 2010 Oct 28 |
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Nigericin-mediated liposome loading of topotecan: is nigericin a potential drug release regulator? | 2010 Oct 31 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 23:28:29 UTC 2023
by
admin
on
Wed Jul 05 23:28:29 UTC 2023
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Record UNII |
L8XED79U3U
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C257
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C84186
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M10364
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PRIMARY | Merck Index | ||
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CHEMBL229241
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1370604
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7322
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L8XED79U3U
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5-SULFOSALICYLIC ACID
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97-05-2
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190565
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202-555-6
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68555
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300000018052
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DTXSID7059145
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SALT/SOLVATE -> PARENT | |||
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