Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H6O6S |
Molecular Weight | 218.184 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=C(O)C=CC(=C1)S(O)(=O)=O
InChI
InChIKey=YCPXWRQRBFJBPZ-UHFFFAOYSA-N
InChI=1S/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13)
Molecular Formula | C7H6O6S |
Molecular Weight | 218.184 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Sulfosalicylic acid dihydrate is a polyfunctional metal chelating ligand that may be used as a metal scavenger.to form metal coordination complexes. Sulfosalicylic acid forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. Proteins are precipitated upon complexation with 5-Sulfosalicylic acid, allowing the qualitative analysis of the resultant turbidity formed in a sample by these complexes leaving solution. Protein precipitation with 5-Sulfosalicylic acid has also been employed as a preparative measure for removing proteins prior to chromatographic analysis.
Approval Year
PubMed
Title | Date | PubMed |
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Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. | 2001 Jan |
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Determination of selenium sulfide using 1,3-dibromo-5,5-dimethylhydantoin (DBH). Analytical methods of pharmacopeias with DBH in respect to environmental and economical concern Part 11. | 2002 Apr 15 |
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Effects of Fe(III) chemical speciation on dissimilatory Fe(III) reduction by Shewanella putrefaciens. | 2002 Feb 1 |
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Mutational analysis of the metabolism of 2,6-naphthalenedisulfonate by Pigmentiphaga sp. NDS-2. | 2003 |
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Potentiometric membrane sensors based on zirconyl(IV) phthalocyanine for detection of sulfosalicylic acid. | 2004 May 28 |
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Equilibrium studies on chromium(III) complexes of salicylic acid and salicylic acid derivatives in aqueous solution. | 2004 Nov |
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Indirect photometric assay determination of gabapentin in bulk drug and capsules by capillary electrophoresis. | 2004 Nov 15 |
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Stoichiometry, stability constants and coordination geometry of Eu(III) 5-sulfosalicylate complex in aqueous system-A TRLIFS study. | 2004 Nov 7 |
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Simultaneous determination of L-arginine and its mono- and dimethylated metabolites in human plasma by high-performance liquid chromatography-mass spectrometry. | 2004 Oct |
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The role of benzoate secreted by Desulfotomaculum acetoxidans DSM 771 in sulfate uptake. | 2005 |
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Comparison of gene expression signatures of diamide, H2O2 and menadione exposed Aspergillus nidulans cultures--linking genome-wide transcriptional changes to cellular physiology. | 2005 Dec 20 |
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Hydrogen bonding in 1:1 proton-transfer compounds of 5-sulfosalicylic acid with 4-X-substituted anilines (X = F, Cl or Br). | 2005 Feb |
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Phenolic compounds, sodium salicylate and related compounds, as inhibitors of tumor cell growth and inducers of apoptosis in mouse leukemia L1210 cells. | 2005 Jan-Feb |
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Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar. | 2005 Jul 11 |
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Photocatalytic degradation of p-nitrophenol on nanometer size titanium dioxide surface modified with 5-sulfosalicylic acid. | 2005 Oct |
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High-throughput metal susceptibility testing of microbial biofilms. | 2005 Oct 3 |
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Layered structures in proton-transfer compounds of 5-sulfosalicylic acid with the aromatic polyamines 2,6-diaminopyridine and 1,4-phenylenediamine. | 2005 Sep |
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In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. | 2006 Aug 16 |
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Serial separation of cations and anions by ion chromatography using the peak parking technique and sulfosalicylic acid as the eluent. | 2006 Feb |
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Lack of evidence for reduced prefrontal cortical serotonin and dopamine efflux after acute tryptophan depletion. | 2007 Dec |
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2-Carboxy-quinolinium-2,4,6-trinitro-benzene-sulfonate-quinolinium-2-carboxyl-ate (1/1/1). | 2007 Dec 6 |
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Tunable separation of anions and cations by column switching in ion chromatography. | 2007 Mar 15 |
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Different effects of angiotensin converting enzyme inhibitors on endothelin-1 and nitric oxide balance in human vascular endothelial cells: evidence of an oxidant-sensitive pathway. | 2008 |
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Synthesis and characterization of conducting polyaniline 5-sulfosalicylate nanotubes. | 2008 Apr 2 |
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Liquid chromatographic fluorescence determination of amino acids in plasma and urine after derivatization with phanquinone. | 2008 Feb |
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The toxic function of cesium 5-sulfosalicylate based on the investigation of its trans-erythrocytes membrane behaviors and morphological properties. | 2008 Feb 15 |
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Pyrazine-diium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate. | 2008 Jun 19 |
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1-Hydroxy-ethyl-2-methyl-5-nitro-imidazolium 3-carb-oxy-4-hydroxy-benzene-sulfonate. | 2008 Jun 25 |
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4-Carboxy-pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate. | 2008 Jun 7 |
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In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. | 2008 Oct 15 |
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4,4'-Methyl-enedianilinium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) monohydrate. | 2008 Sep 17 |
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Poly[[diaqua(μ(2)-4,4'-dipyridyl sulfide-κN:N')(4,4'-dipyridyl sulfide-κN)(2-hydroxy-5-sulfonatobenzoato-κO)nickel(II)] dihydrate]. | 2008 Sep 20 |
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4-(4-Carb-oxy-1,3-thia-zol-2-yl)pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate dihydrate. | 2008 Sep 30 |
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Bis[μ-1,2-bis-(1H-imidazol-1-ylmeth-yl)benzene-κN:N]disilver(I) 3-carboxyl-ato-4-hydroxy-benzene-sulfonate methanol solvate trihydrate. | 2009 Aug 8 |
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3,3'-(p-Phenyl-enedimethyl-ene)di-imidazol-1-ium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate. | 2009 Jan 23 |
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Diaqua-bis(1,10-phenanthroline-κN,N')zinc(II) 2-hydr-oxy-5-sulfonatobenzoate tetra-hydrate. | 2009 Jan 31 |
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Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats. | 2009 Jul |
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COOH-terminal truncations and site-directed mutations enhance thermostability and chaperone-like activity of porcine alphaB-crystallin. | 2009 Jul 28 |
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Poly[aqua-(μ(5)-2-oxido-4-sulfonato-benzoato)lanthanum(III)]. | 2009 Mar 11 |
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o-Phenyl-enediammonium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate). | 2009 Nov 21 |
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Guanidinium quinoline-2-carboxyl-ate. | 2009 Nov 25 |
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4-(2-Hydroxy-ethyl)anilinium 3-carb-oxy-4-hydroxy-benzene-sulfonate monohydrate. | 2009 Nov 25 |
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Hexaaqua-zinc(II) bis-(4-hydroxy-benzene-sulfonate) dihydrate. | 2009 Oct 10 |
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Aqua-(2-hydr-oxy-5-sulfonatobenzoato-κO)bis-(2-phenyl-1H-1,3,7,8-tetra-aza-cyclo-penta-[l]phenanthrene-κN,N)zinc(II). | 2009 Oct 3 |
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Reduction of ischemic and oxidative damage to the hypothalamus by hyperbaric oxygen in heatstroke mice. | 2010 |
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Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection. | 2010 Aug 27 |
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Effect of dietary fats on oxidative-antioxidative status of blood in rats. | 2010 Jul |
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[Hydrogen bis-(1,2,4-triazole)] 1,2,4-triazolium bis-(3-carb-oxy-4-hy-droxy-benzene-sulfonate) 1,2,4-triazole disolvate. | 2010 Jul 17 |
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Nigericin-mediated liposome loading of topotecan: is nigericin a potential drug release regulator? | 2010 Oct 31 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:16:02 GMT 2025
by
admin
on
Mon Mar 31 18:16:02 GMT 2025
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Record UNII |
L8XED79U3U
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C257
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C84186
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m10364
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CHEMBL229241
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1370604
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7322
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L8XED79U3U
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5-SULFOSALICYLIC ACID
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97-05-2
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190565
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202-555-6
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68555
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300000018052
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DTXSID7059145
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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SOLVATE->ANHYDROUS | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT | |||
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ACTIVE MOIETY |