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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6O6S
Molecular Weight 218.184
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFOSALICYLIC ACID

SMILES

OC(=O)C1=C(O)C=CC(=C1)S(O)(=O)=O

InChI

InChIKey=YCPXWRQRBFJBPZ-UHFFFAOYSA-N
InChI=1S/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13)

HIDE SMILES / InChI
Molecular Formula C7H6O6S
Molecular Weight 218.184
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sulfosalicylic acid dihydrate is a polyfunctional metal chelating ligand that may be used as a metal scavenger.to form metal coordination complexes. Sulfosalicylic acid forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. Proteins are precipitated upon complexation with 5-Sulfosalicylic acid, allowing the qualitative analysis of the resultant turbidity formed in a sample by these complexes leaving solution. Protein precipitation with 5-Sulfosalicylic acid has also been employed as a preparative measure for removing proteins prior to chromatographic analysis.

Approval Year

1996
224
PubMed

PubMed

TitleDatePubMed
Acetaminophen induces apoptosis in rat cortical neurons.
2010-12-10
Identification of protonation state by XPS, solid-state NMR, and DFT: characterization of the nature of a new theophylline complex by experimental and computational methods.
2010-11-11
Salts of aromatic amines: crystal structures, spectroscopic and non-linear optical properties.
2010-11
Nigericin-mediated liposome loading of topotecan: is nigericin a potential drug release regulator?
2010-10-31
Polynuclear complexes of macrocyclic oxamide with 5-sulfosalicylate: syntheses, crystal structures and magnetic properties.
2010-10-28
A simple colorimetric FIA method for the determination of pyrite oxidation rates.
2010-10-15
2-Amino-5-bromo-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-08-28
Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection.
2010-08-27
2-Amino-5-chloro-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-08-18
2-Amino-5-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-07-31
2-Amino-4-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate monohydrate.
2010-07-24
[Hydrogen bis-(1,2,4-triazole)] 1,2,4-triazolium bis-(3-carb-oxy-4-hy-droxy-benzene-sulfonate) 1,2,4-triazole disolvate.
2010-07-17
Effect of dietary fats on oxidative-antioxidative status of blood in rats.
2010-07
Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage.
2010-07
The T1405N carbamoyl phosphate synthetase polymorphism does not affect plasma arginine concentrations in preterm infants.
2010-05-25
Binary and Ternary Heterometallic (La3+, Gd3+, Y3+)-Eu3+ Functionalized SBA-15 Mesoporous Hybrids: Chemically Bonded Assembly and Photoluminescence.
2010-05-16
Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.
2010-04-23
Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass.
2010-02-12
Reduction of ischemic and oxidative damage to the hypothalamus by hyperbaric oxygen in heatstroke mice.
2010
Guanidinium quinoline-2-carboxyl-ate.
2009-11-25
4-(2-Hydroxy-ethyl)anilinium 3-carb-oxy-4-hydroxy-benzene-sulfonate monohydrate.
2009-11-25
o-Phenyl-enediammonium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate).
2009-11-21
Hexaaqua-zinc(II) bis-(4-hydroxy-benzene-sulfonate) dihydrate.
2009-10-10
Aqua-(2-hydr-oxy-5-sulfonatobenzoato-κO)bis-(2-phenyl-1H-1,3,7,8-tetra-aza-cyclo-penta-[l]phenanthrene-κN,N)zinc(II).
2009-10-03
Proton transfer versus nontransfer in compounds of the diazo-dye precursor 4-(phenyldiazenyl)aniline (aniline yellow) with strong organic acids: the 5-sulfosalicylate and the dichroic benzenesulfonate salts, and the 1:2 adduct with 3,5-dinitrobenzoic acid.
2009-10
Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments.
2009-10
Removal of transition metal ions from aqueous solutions by adsorption onto a novel silica gel matrix composite adsorbent.
2009-09-30
Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke.
2009-09-03
Bismuth(III) 5-sulfosalicylate complexes: structure, solubility and activity against Helicobacter pylori.
2009-08-28
Bis[μ-1,2-bis-(1H-imidazol-1-ylmeth-yl)benzene-κN:N]disilver(I) 3-carboxyl-ato-4-hydroxy-benzene-sulfonate methanol solvate trihydrate.
2009-08-08
COOH-terminal truncations and site-directed mutations enhance thermostability and chaperone-like activity of porcine alphaB-crystallin.
2009-07-28
Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats.
2009-07
Poly[aqua-(μ(5)-2-oxido-4-sulfonato-benzoato)lanthanum(III)].
2009-03-11
Three-dimensional networks in the 1:2 organic salts 2,2'-biimidazolium bis(3-carboxy-4-hydroxybenzenesulfonate) and 2,2'-bibenzimidazolium bis(3-carboxy-4-hydroxybenzenesulfonate) trihydrate.
2009-02
Diaqua-bis(1,10-phenanthroline-κN,N')zinc(II) 2-hydr-oxy-5-sulfonatobenzoate tetra-hydrate.
2009-01-31
3,3'-(p-Phenyl-enedimethyl-ene)di-imidazol-1-ium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate.
2009-01-23
Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis.
2009
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.
2008-10-15
4-(4-Carb-oxy-1,3-thia-zol-2-yl)pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate dihydrate.
2008-09-30
Poly[[diaqua(μ(2)-4,4'-dipyridyl sulfide-κN:N')(4,4'-dipyridyl sulfide-κN)(2-hydroxy-5-sulfonatobenzoato-κO)nickel(II)] dihydrate].
2008-09-20
4,4'-Methyl-enedianilinium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) monohydrate.
2008-09-17
1-Hydroxy-ethyl-2-methyl-5-nitro-imidazolium 3-carb-oxy-4-hydroxy-benzene-sulfonate.
2008-06-25
Pyrazine-diium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate.
2008-06-19
4-Carboxy-pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate.
2008-06-07
Synthesis and characterization of conducting polyaniline 5-sulfosalicylate nanotubes.
2008-04-02
Different effects of angiotensin converting enzyme inhibitors on endothelin-1 and nitric oxide balance in human vascular endothelial cells: evidence of an oxidant-sensitive pathway.
2008
2-Carboxy-quinolinium-2,4,6-trinitro-benzene-sulfonate-quinolinium-2-carboxyl-ate (1/1/1).
2007-12-06
Tunable separation of anions and cations by column switching in ion chromatography.
2007-03-15
Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease.
2005-04
Potentiometric membrane sensors based on zirconyl(IV) phthalocyanine for detection of sulfosalicylic acid.
2004-05-28
Patents

Patents

20040019143
3
JP2000157296A
3
JPH08114599A
5
JPH09176206A
5
JPH10293131A
5
JPS55149131A
5
JPS5849779A
3
JPS60123408A
5
JPS629272A
5
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:16:02 GMT 2025
Edited
by admin
on Mon Mar 31 18:16:02 GMT 2025
Record UNII
L8XED79U3U
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
NSC-190565
Preferred Name English
SULFOSALICYLIC ACID
MI   WHO-DD  
Systematic Name English
2-HYDROXYBENZOIC-5-SULFONIC ACID
Common Name English
2-HYDROXY-5-SULFOBENZOIC ACID
Systematic Name English
5-SULFOSALICYLIC ACID
Systematic Name English
SALICYLSULFONIC ACID
Systematic Name English
SULFOSALICYLIC ACID [MI]
Common Name English
3-CARBOXY-4-HYDROXYBENZENESULFONIC ACID
Systematic Name English
Sulfosalicylic acid [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C257
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C84186
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
MERCK INDEX
m10364
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY Merck Index
ChEMBL
CHEMBL229241
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
RXCUI
1370604
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
PUBCHEM
7322
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
FDA UNII
L8XED79U3U
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
WIKIPEDIA
5-SULFOSALICYLIC ACID
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
CAS
97-05-2
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
NSC
190565
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
202-555-6
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
CHEBI
68555
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
SMS_ID
300000018052
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
EPA CompTox
DTXSID7059145
Created by admin on Mon Mar 31 18:16:02 GMT 2025 , Edited by admin on Mon Mar 31 18:16:02 GMT 2025
PRIMARY
Related Record Type Details
Structure of METHENAMINE SULFOSALICYLATE MONOHYDRATE
SALT/SOLVATE -> PARENT
SULFOSALICYLATE
SUB_CONCEPT->SUBSTANCE
Structure of METHENAMINE SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Structure of SULFOSALICYLIC ACID DIHYDRATE
SOLVATE->ANHYDROUS
Structure of SULFOSALICYLIC ACID DIHYDRATE
SALT/SOLVATE -> PARENT
Structure of DISODIUM SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Structure of MECLOCYCLINE SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Structure of METHACYCLINE 5-SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Structure of DOXYCYCLINE SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of SULFOSALICYLIC ACID
ACTIVE MOIETY
NIH
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