U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 20:12:12 GMT 2023
Edited
by admin
on Sat Dec 16 20:12:12 GMT 2023
Nucleic Acid Type mRNA
Nucleic Acid Subtype
Sequence Type COMPLETE
Record UNII
L8HDH9IB06
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AUTOGENE CEVUMERAN
INN  
Official Name English
Autogene cevumeran [WHO-DD]
Common Name English
BNT122
Code English
RO7198457
Code English
RG-6180
Code English
BNT-122
Code English
AUTOGENE CEVUMERAN [USAN]
Common Name English
RNA (recombinant 5′-[1,2-[m7Gm-(5′→5′)-p-[P(R)]-sp-p-G]]-capped 5′-UTR (human α-globin RNA-Kozak)/secretory signal peptide sec2.0-specifying/patient-specific tumor neoantigen-specifying insertion site/major histocompatibility complex class I t
Common Name English
RG 6180
Code English
A 5'-capped single-stranded messenger RNA (mRNA) construct for the expression of patient-specific tumour neoantigens comprising a 5'-cap, a 5'-untranslated region derived from human alpha-globin mRNA, an optimised Kozak sequence, sequences encoding a sec
Common Name English
RO-7198457
Code English
autogene cevumeran [INN]
Common Name English
Code System Code Type Description
INN
11177
Created by admin on Sat Dec 16 20:12:12 GMT 2023 , Edited by admin on Sat Dec 16 20:12:12 GMT 2023
PRIMARY
CAS
2365453-34-3
Created by admin on Sat Dec 16 20:12:12 GMT 2023 , Edited by admin on Sat Dec 16 20:12:12 GMT 2023
PRIMARY
FDA UNII
L8HDH9IB06
Created by admin on Sat Dec 16 20:12:12 GMT 2023 , Edited by admin on Sat Dec 16 20:12:12 GMT 2023
PRIMARY
USAN
HI-204
Created by admin on Sat Dec 16 20:12:12 GMT 2023 , Edited by admin on Sat Dec 16 20:12:12 GMT 2023
PRIMARY
NCI_THESAURUS
C175745
Created by admin on Sat Dec 16 20:12:12 GMT 2023 , Edited by admin on Sat Dec 16 20:12:12 GMT 2023
PRIMARY
Sugar Site Range Site Count
D-Ribose (RNA) 1_2-1_740 739 / 739
Linkage Site Range Site Count
Phosphate 1_2-1_739 738 / 738
Related Record Type Details
ACTIVE MOIETY
targets antigen-presenting cells to induce an immune response
Name Property Type Amount Referenced Substance Defining Parameters References
Poly A NUCLEIC ACID FEATURE
FI NUCLEIC ACID FEATURE
hAG-Kozak NUCLEIC ACID FEATURE
secretion signal sequence NUCLEIC ACID FEATURE
transmembrane and cytoplasmic domains of MHC class I molecule NUCLEIC ACID FEATURE