U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 08:46:52 GMT 2025
Edited
by admin
on Wed Apr 02 08:46:52 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
L62556GPXB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TEBOTELIMAB
INN  
Official Name English
tebotelimab [INN]
Preferred Name English
Tebotelimab [WHO-DD]
Common Name English
MABFRAG HUMAN (FC)MABFRAG HUMANIZED (FAB) ANTI Q15116 (PDCD1_HUMAN)MABFRAG HUMANIZED (FAB) ANTI P18627 (LAG3_HUMAN) (MGD013)
Common Name English
MGD013 DUAL-AFFINITY RE-TARGETING (DART)
Common Name English
MGD-013
Common Name English
IMMUNOGLOBULIN G4 (24-ARGININE,278-PROLINE), BISPECIFIC TETRAVALENT, ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3) (HUMAN-MUS MUSCULUS MONOCLONAL MGD013 LIGHT CHAIN VL FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER 1) FUSION PROTEIN WITH IMMUNOGLOBU
Common Name English
MGD013
Common Name English
MGD013 (PD-1 X LAG-3)
Common Name English
Code System Code Type Description
CAS
2245725-04-4
Created by admin on Wed Apr 02 08:46:52 GMT 2025 , Edited by admin on Wed Apr 02 08:46:52 GMT 2025
PRIMARY
NCI_THESAURUS
C143957
Created by admin on Wed Apr 02 08:46:52 GMT 2025 , Edited by admin on Wed Apr 02 08:46:52 GMT 2025
PRIMARY
INN
11338
Created by admin on Wed Apr 02 08:46:52 GMT 2025 , Edited by admin on Wed Apr 02 08:46:52 GMT 2025
PRIMARY
FDA UNII
L62556GPXB
Created by admin on Wed Apr 02 08:46:52 GMT 2025 , Edited by admin on Wed Apr 02 08:46:52 GMT 2025
PRIMARY
SMS_ID
300000024158
Created by admin on Wed Apr 02 08:46:52 GMT 2025 , Edited by admin on Wed Apr 02 08:46:52 GMT 2025
PRIMARY
From To
1_23 1_88
1_137 1_211
1_276 2_276
1_279 2_279
1_237 3_240
1_245 3_248
1_311 1_371
1_417 1_475
2_23 2_88
2_137 2_211
2_237 4_240
2_245 4_248
2_311 2_371
2_417 2_475
3_23 3_92
3_141 3_215
4_141 4_215
4_23 4_92
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_347
N 2_347
Related Record Type Details
LYMPHOCYTE ACTIVATION GENE 3 PROTEIN
TARGET -> INHIBITOR
PROGRAMMED CELL DEATH PROTEIN 1
TARGET -> INHIBITOR
Related Record Type Details
TEBOTELIMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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