TEBOTELIMAB

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 17:04:48 UTC 2023` Edited by `admin` on `Sat Dec 16 17:04:48 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	L62556GPXB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TEBOTELIMAB

Official Name

English

Tebotelimab [WHO-DD]

Common Name

English

MABFRAG HUMAN (FC)MABFRAG HUMANIZED (FAB) ANTI Q15116 (PDCD1_HUMAN)MABFRAG HUMANIZED (FAB) ANTI P18627 (LAG3_HUMAN) (MGD013)

Common Name

English

MGD013 DUAL-AFFINITY RE-TARGETING (DART)

Common Name

English

MGD-013

Common Name

English

IMMUNOGLOBULIN G4 (24-ARGININE,278-PROLINE), BISPECIFIC TETRAVALENT, ANTI-(HUMAN LYMPHOCYTE ACTIVATION GENE-3) (HUMAN-MUS MUSCULUS MONOCLONAL MGD013 LIGHT CHAIN VL FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER 1) FUSION PROTEIN WITH IMMUNOGLOBU

Common Name

English

MGD013

Common Name

English

tebotelimab [INN]

Common Name

English

MGD013 (PD-1 X LAG-3)

Common Name

English

Code System Code Type Description

CAS

2245725-04-4

Created by admin on Sat Dec 16 17:04:48 UTC 2023 , Edited by admin on Sat Dec 16 17:04:48 UTC 2023

PRIMARY

NCI_THESAURUS

C143957

Created by admin on Sat Dec 16 17:04:48 UTC 2023 , Edited by admin on Sat Dec 16 17:04:48 UTC 2023

PRIMARY

INN

11338

Created by admin on Sat Dec 16 17:04:48 UTC 2023 , Edited by admin on Sat Dec 16 17:04:48 UTC 2023

PRIMARY

FDA UNII

L62556GPXB

Created by admin on Sat Dec 16 17:04:48 UTC 2023 , Edited by admin on Sat Dec 16 17:04:48 UTC 2023

PRIMARY

From	To
1_23	1_88
1_137	1_211
1_276	2_276
1_279	2_279
1_237	3_240
1_245	3_248
1_311	1_371
1_417	1_475
2_23	2_88
2_137	2_211
2_237	4_240
2_245	4_248
2_311	2_371
2_417	2_475
3_23	3_92
3_141	3_215
4_141	4_215
4_23	4_92

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_347
N	2_347

Related Record Type Details


					AK0JDV1ZK5

LYMPHOCYTE ACTIVATION GENE 3 PROTEIN

TARGET -> INHIBITOR


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Related Record Type Details


					L62556GPXB

TEBOTELIMAB

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL