METRONIDAZOLE PHOSPHATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H10N3O6P
Molecular Weight	251.1339
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC=C(N1CCOP(O)(O)=O)[N+]([O-])=O

InChI

InChIKey=GFFOAZOYBIIJHI-UHFFFAOYSA-N

InChI=1S/C6H10N3O6P/c1-5-7-4-6(9(10)11)8(5)2-3-15-16(12,13)14/h4H,2-3H2,1H3,(H2,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C6H10N3O6P
Molecular Weight	251.1339
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7086647

Metronidazole phosphate is a water-soluble prodrug of metronidazole.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Characterization of metronidazole-phosphate, a water-soluble metronidazole derivative, as a radiosensitizer of hypoxic cells.	1979 May	442119
Metronidazole phosphate--a water-soluble prodrug for parenteral solutions of metronidazole.	1982 Apr	7086647
A comparison of metronidazole distribution following intravenous metronidazole and metronidazole phosphate disodium in mice.	1992	1424643
[Study on hydrolytic kinetics of metronidazole-phosphate in rabbit plasma by HPLC].	1993 Mar	8340082

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:26:15 GMT 2023` Edited by `admin` on `Fri Dec 15 15:26:15 GMT 2023`
Record UNII	L500PR95QA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METRONIDAZOLE PHOSPHATE

Official Name

English

U-54,555

Code

English

2-Methyl-5-nitroimidazole-1-ethanol dihydrogen phosphate (ester)

Common Name

English

METRONIDAZOLE PHOSPHATE [USAN]

Common Name

English

1H-IMIDAZOLE-1-ETHANOL, 2-METHYL-5-NITRO-, DIHYDROGEN PHOSPHATE (ESTER)

Common Name

English

U-54555

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C279