ACETYL HEXAPEPTIDE-8 (ARGIRELINE®), a hexapeptide Ac-EEMQRR-NH2, is an anti-wrinkling agent. It significantly inhibits neurotransmitter release with a potency similar to that of botulinum toxin. ACETYL HEXAPEPTIDE-8 (ARGIRELINE®) is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles.
Originator
Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 20:23:16 GMT 2023
by
admin
on
Sat Dec 16 20:23:16 GMT 2023
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| Protein Type | PEPTIDE |
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
L4EL31FWIL
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Code System | Code | Type | Description | ||
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616204-22-9
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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ACETYL HEXAPEPTIDE-3
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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11228338
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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DB11709
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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L4EL31FWIL
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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1314329
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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PRIMARY | RxNorm | ||
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L4EL31FWIL
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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DTXSID201021291
Created by
admin on Sat Dec 16 20:23:16 GMT 2023 , Edited by admin on Sat Dec 16 20:23:16 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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