LACTOFEN

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H15ClF3NO7
Molecular Weight	461.773
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C(C)OC(=O)C1=C(C=CC(OC2=C(Cl)C=C(C=C2)C(F)(F)F)=C1)[N+]([O-])=O

InChI

InChIKey=CONWAEURSVPLRM-UHFFFAOYSA-N

InChI=1S/C19H15ClF3NO7/c1-3-29-17(25)10(2)30-18(26)13-9-12(5-6-15(13)24(27)28)31-16-7-4-11(8-14(16)20)19(21,22)23/h4-10H,3H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H15ClF3NO7
Molecular Weight	461.773
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Induction of hepatic peroxisome proliferation in mice by lactofen, a diphenyl ether herbicide.	1988 Mar 30	3354002
Lactofen induces isoflavone accumulation and glyceollin elicitation competency in soybean.	2003 Mar	12590114
Effects of pesticides on yeasts isolated from agricultural soil.	2003 Nov-Dec	14713165
The diphenylether herbicide lactofen induces cell death and expression of defense-related genes in soybean.	2005 Dec	16299178
Herbicide effects on cuticle ultrastructure in Eleusine indica and Portulaca oleracea.	2006 Apr	16845829
Enantiomeric resolution of chiral pesticides by high-performance liquid chromatography.	2006 Mar 8	16506803
Determination of diphenylether herbicides in water samples by solid-phase microextraction coupled to liquid chromatography.	2006 Nov	17313105
Chiral separations of pesticide enantiomers by high-performance liquid chromatography using cellulose triphenylcarbamate chiral stationary phase.	2006 Nov-Dec	17254369
Enantiomeric separation of chiral pesticides by high performance liquid chromatography on cellulose tris-3,5-dimethyl carbamate stationary phase under reversed phase conditions.	2007 Feb	17396588
Soil amendment: a technique for soil remediation of lactofen.	2007 Jul	17599224
PPARalpha- and DEHP-Induced Cancers.	2008	18769559
The chiral resolution of pesticides on amylose-tris(3,5-dimethylphenylcarbamate) CSP by HPLC and the enantiomeric identification by circular dichroism.	2008 Jan	17957825
Biodegradation of fomesafen by strain Lysinibacillus sp. ZB-1 isolated from soil.	2009 Dec	19846192
Influence of soil properties on the enantioselective dissipation of the herbicide lactofen in soils.	2009 Jul 8	19507858
In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project.	2010 Apr	20368123
Enantioselective degradation in sediment and aquatic toxicity to Daphnia magna of the herbicide lactofen enantiomers.	2010 Feb 24	20088506
Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.	2010 Mar 15	20143881
Biotransformation of the diphenyl ether herbicide lactofen and purification of a lactofen esterase from Brevundimonas sp. LY-2.	2010 Sep 8	20712347
Environmental impact on vascular development predicted by high-throughput screening.	2011 Nov	21788198

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:04:02 GMT 2023` Edited by `admin` on `Sat Dec 16 09:04:02 GMT 2023`
Record UNII	L44N8UV47O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LACTOFEN

Common Name

English

5-(2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY)-2-NITROBENZOIC ACID 2-ETHOXY-1-METHYL-2-OXOETHYL ESTER

Systematic Name

English

PHOENIX (HERBICIDE)

Common Name

English

1'-(CARBOETHOXY)ETHYL 5-(2-CHLORO-4- (TRIFLUOROMETHYL)PHENOXY)-2-NITROBENZOATE

Common Name

English

COBRA HERBICIDE [HSDB]

Common Name

English

BENZOIC ACID, 5-(2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY)-2- NITRO-, 2-ETHOXY-1-METHYL-2-OXOETHYL ESTER

Common Name

English

2-ETHOXY-1-METHYL-2-OXOETHYL 5-(2-CHLORO-4- (TRIFLUOROMETHYL)PHENOXY)-2 NITROBENZOATE, (±)-

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

128888