Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 20:08:40 GMT 2023
by
admin
on
Sat Dec 16 20:08:40 GMT 2023
|
| Protein Type | PEPTIDE |
| Protein Sub Type | |
| Sequence Origin | SYNTHETIC |
| Sequence Type | COMPLETE |
| Record UNII |
L35G38C9KP
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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1309437-08-8
Created by
admin on Sat Dec 16 20:08:40 GMT 2023 , Edited by admin on Sat Dec 16 20:08:40 GMT 2023
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PRIMARY | |||
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L35G38C9KP
Created by
admin on Sat Dec 16 20:08:40 GMT 2023 , Edited by admin on Sat Dec 16 20:08:40 GMT 2023
|
PRIMARY | |||
|
162625099
Created by
admin on Sat Dec 16 20:08:40 GMT 2023 , Edited by admin on Sat Dec 16 20:08:40 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
HB1518 is an anti-UV phototoxic pentapeptide that activates cell cycle checkpoints when keratinocytes are exposed to DNA-damaging elements (mutagens) such as ultraviolet (UV) irradiation, thereby impeding cell division. After mutagen-induced damage, the cell cycle is arrested in the G2 phase, allowing time for DNA repair. However, if checkpoint processes are disrupted or inhibited, cancers (such as DNA mutations) occur less frequently. HB1518 can activate cell cycle regulatory proteins by blocking phosphorylation and avoid mutagen-induced cell or tissue toxicity
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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