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Details

Stereochemistry UNKNOWN
Molecular Formula C12H14N2O3
Molecular Weight 234.2512
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPROQUALONE, (+)-

SMILES

CC1=NC2=CC=CC=C2C(=O)N1CC(O)CO

InChI

InChIKey=NTGLQWGMESPVBV-UHFFFAOYSA-N
InChI=1S/C12H14N2O3/c1-8-13-11-5-3-2-4-10(11)12(17)14(8)6-9(16)7-15/h2-5,9,15-16H,6-7H2,1H3

HIDE SMILES / InChI

Molecular Formula C12H14N2O3
Molecular Weight 234.2512
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Diproqualone was used primarily for the treatment of inflammatory pain associated with osteoarthritis. The analgesic activity of diproqualoneis synergistic with that of noramidopyrine. It also display anti-inflammatory action in the rat, inhibiting plantar edema with dextran or serotonin, atopic edema from ovalbumin, etc. It has spasmolytic, anticholinergic and antihistaminic action in higher doses. It is not hypnotic and has no anticonvulsant effects. The therapeutic symptoms for diproqualone are all types of pain: postoperative, posttraumatic, dental, neuritis, anti-inflammatory arthritis, etc.

Approval Year

PubMed

Substance Class Chemical
Record UNII
L2Y2CV3EW7
Record Status Validated (UNII)
Record Version