U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:11:42 GMT 2023
Edited
by admin
on Sat Dec 16 13:11:42 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
L23181O7GB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HEMOGLOBULIN S
Common Name English
HBS
Common Name English
HEMOGLOBIN S
Common Name English
HB S
Common Name English
HEMOGLOBULIN, SICKLED
Common Name English
HB-S
Common Name English
SICKLED HEMOGLOBULIN
Common Name English
Code System Code Type Description
FDA UNII
L23181O7GB
Created by admin on Sat Dec 16 13:11:42 GMT 2023 , Edited by admin on Sat Dec 16 13:11:42 GMT 2023
PRIMARY
Related Record Type Details
ACTIVATOR -> TARGET
GBT021601 binds to HbS and increases its oxygen (O2) affinity, thereby stabilizing the oxygenated hemoglobin (oxyHb) state and inhibiting HbS polymerization
INHIBITOR OF AGGREGATION->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL