U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:17:07 GMT 2023
Edited
by admin
on Sat Dec 16 14:17:07 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
L15LO3W1XX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PIVEKIMAB SUNIRINE
INN   USAN  
Official Name English
IMGN-632
Code English
IMGN632
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL3RA (INTERLEUKIN 3 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN 3 RECEPTOR, ALPHA (LOW AFFINITY), CD123)), MONOCLONAL ANTIBODY, CONJUGATED WITH SULFONATED DGN549-C, A CYTOTOXIC INDOLOBENZODIAZEPINE DIMER BONDED TO A P
Common Name English
AN ANTIBODY DRUG CONJUGATE CONSISTING OF HUMANIZED ANTI-CD123 ANTIBODY G4723A LINKED WITH DNA ALKYLATING AGENT DGN549C FOR AML AND OTHER CD123-POS. MALIGNANCIES
Common Name English
Pivekimab sunirine [WHO-DD]
Common Name English
PIVEKIMAB SUNIRINE [USAN]
Common Name English
pivekimab sunirine [INN]
Common Name English
Code System Code Type Description
INN
11695
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
PRIMARY
CAS
2417174-95-7
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
PRIMARY
USAN
JK-169
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
PRIMARY
NCI_THESAURUS
C184834
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
PRIMARY
FDA UNII
L15LO3W1XX
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
PRIMARY
CAS
2364499-35-2
Created by admin on Sat Dec 16 14:17:07 GMT 2023 , Edited by admin on Sat Dec 16 14:17:07 GMT 2023
NO STRUCTURE GIVEN
From To
4_134 4_194
2_371 2_429
2_265 2_325
3_134 3_194
2_22 2_96
2_148 2_204
1_148 1_204
2_224 4_214
1_224 3_214
1_233 2_233
1_230 2_230
1_22 1_96
3_23 3_88
4_23 4_88
1_265 1_325
1_371 1_429
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL