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Details

Stereochemistry ACHIRAL
Molecular Formula Ca.HO4P
Molecular Weight 136.057
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANHYDROUS DIBASIC CALCIUM PHOSPHATE

SMILES

[Ca++].OP([O-])([O-])=O

InChI

InChIKey=FUFJGUQYACFECW-UHFFFAOYSA-L
InChI=1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

HIDE SMILES / InChI

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO4P
Molecular Weight 95.9793
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Calcium iodide (chemical formula CaI2) is the ionic compound of calcium and iodine, used in cat food as a source of iodine This colourless deliquescent solid is a salt that is highly soluble in water. Calcium iodide properties are similar to those for related salts, such as calcium chloride. Calcium iodide is also used in photography.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Hypocalcemia, chronic (treatment) ā€” Oral calcium supplements provide a source of calcium ion for treating calcium depletion occurring in conditions such as chronic hypoparathyroidism, pseudohypoparathyroidism, osteomalacia, rickets, chronic renal failure, and hypocalcemia secondary to the administration of anticonvulsant medications. When chronic hypocalcemia is due to vitamin D deficiency, oral calcium salts may be administered concomitantly with vitamin D analogs. However, calcium phosphate should not be used in patients with hypoparathyroidism or renal failure, since phosphate levels may be too high and giving more phosphate would exacerbate the condition. Calcium supplements should not be used in hyperparathyroidism, unless the need for a calcium supplement is high and the patient is carefully monitored. For treatment of hypocalcemia, supplementation is preferred
PubMed

PubMed

TitleDatePubMed
Studies on the calcemic effect of intravenous secretin in humans.
1975 Jun
Expression and functional analysis of chemokine receptors in human peripheral blood leukocyte populations.
2001 Apr 7
Endothelin-induced changes of secondary messengers in cultured corneal endothelial cells.
2001 Aug
Metal ion-independent association of factor VIII subunits and the roles of calcium and copper ions for cofactor activity and inter-subunit affinity.
2001 Aug 28
Complement activation in factor D-deficient mice.
2001 Dec 4
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line.
2001 Jul
Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine.
2001 Jul
Analysis of the native quaternary structure of vanilloid receptor 1.
2001 Jul 27
Endothelin- and sarafotoxin-induced receptor-mediated calcium mobilization in a clonal murine osteoblast-like cell line, MC3T3-E1/B.
2001 Jun
[Acute renal failure caused by hypercalcemia].
2001 Jun 10
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors.
2001 Mar 15
RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses.
2001 Mar 27
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities.
2001 Nov
Activating mutations of the calcium-sensing receptor: management of hypocalcemia.
2001 Nov
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors.
2001 Nov 1
Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.
2001 Nov 30
Microarray analysis of differential gene expression in lead-exposed astrocytes.
2001 Oct 1
Replacement of the muscle-specific sarcoplasmic reticulum Ca(2+)-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart.
2001 Oct 26
Regional differences in functional receptor distribution and calcium mobilization in the intact human lens.
2001 Sep
Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism.
2001 Sep
Ameliorative effect of vasopressin-(4-9) through vasopressin V(1A) receptor on scopolamine-induced impairments of rat spatial memory in the eight-arm radial maze.
2001 Sep 7
Cannabinoids attenuate depolarization-dependent Ca2+ influx in intermediate-size primary afferent neurons of adult rats.
2002
Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells.
2002 Dec
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene.
2002 Feb
Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice.
2002 Jan 15
Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones.
2002 Jul
Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium.
2002 Jul
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent.
2002 Jul 5
Human kidney diamine oxidase: heterologous expression, purification, and characterization.
2002 Jun
Expression of functional CCR and CXCR chemokine receptors in podocytes.
2002 Jun 15
Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor.
2002 Mar
Hypertension-related intermyocyte junction remodelling is associated with a higher incidence of low-K(+)-induced lethal arrhythmias in isolated rat heart.
2002 Mar
Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.
2002 Mar 15
Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products.
2002 May 15
Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons.
2002 Nov 4
Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
2002 Sep
Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors.
2002 Sep 15
Effects of endothelin B receptor agonists on amyloid beta protein (25-35)-induced neuronal cell death.
2002 Sep 6
A critical interplay between Ca2+ inhibition and activation by Mg2+ of AC5 revealed by mutants and chimeric constructs.
2002 Sep 6
Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension.
2003 Jan
[Prevention of osteoporosis by foods and dietary supplements. Bioavailability of milk micellar calcium phosphate].
2006 Oct
Henri Moissan: winner of the Nobel Prize for Chemistry 1906.
2006 Oct 20
Dietary calcium source influences body composition, glucose metabolism and hormone levels in a mouse model of postmenopausal obesity.
2009 Jul-Aug
A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans.
2012 Apr
Effect of calcium phosphate and vitamin Dā‚ƒ supplementation on bone remodelling and metabolism of calcium, phosphorus, magnesium and iron.
2014 Jan 17
Long-term remineralizing effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on early caries lesions in vivo: a systematic review.
2014 Jul
Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model--a clinical trial.
2015 Aug 12
Dietary interventions for mineral and bone disorder in people with chronic kidney disease.
2015 Sep 16
Lactose behaviour in the presence of lactic acid and calcium.
2016 Aug
Effects of ultrasound treatment on physico-chemical, functional properties and antioxidant activity of whey protein isolate in the presence of calcium lactate.
2018 Mar
Patents

Sample Use Guides

oral: 500 to 2000 mg elemental calcium a day, in divided doses (bid-qid). inhalation: In a single-blind, phase 1B proof of concept study, 24 subjects were enrolled to sequentially receive three doses of PUR118 (calcium lactate inhalation powder (CLIP) formulation) (5.5 mg, n = 18; 11.0 mg, n = 18; 2.8 mg, n = 16). Each dose was inhaled 3 times (1, 13, 25 h, preceded by 2 puffs salbutamol) before the ozone exposure (250 ppb, 3 h intermittent exercise). Sputum was induced 3 h after the end of exposure.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 17:18:34 UTC 2022
Edited
by admin
on Fri Dec 16 17:18:34 UTC 2022
Record UNII
L11K75P92J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUS
II  
Preferred Name English
ANHYDROUS DIBASIC CALCIUM PHOSPHATE
USP  
Common Name English
CALCIUM PHOSPHATE DIBASIC
WHO-DD  
Common Name English
CALCIUM PHOSPHATE (DIBASIC)
Common Name English
CALCIUM HYDROGEN PHOSPHATE ANHYDROUS
Common Name English
CALCIUM HYDROGEN ORTHOPHOSPHATE
Systematic Name English
DICALCIUM PHOSPHATE
INCI  
INCI  
Official Name English
INS-341(II)
Code English
CALCII HYDROGENOPHOSPHAS [WHO-IP LATIN]
Common Name English
CALCIUM PHOSPHATE, DIBASIC, ANHYDROUS [II]
Common Name English
CALCIUM PHOSPHATE, DIBASIC
HSDB   MI  
Common Name English
CALCIUM PHOSPHATE,DIBASIC [VANDF]
Common Name English
CALCIUM PHOSPHATE, DIBASIC ANHYDROUS
Common Name English
PHOSPHORUS (AS DICALCIUM PHOSPHATE) [VANDF]
Common Name English
CALCIUM MONOHYDROGEN PHOSPHATE
Systematic Name English
PHOSPHORUS (AS CALCIUM PHOSPHATE,DIBASIC) [VANDF]
Common Name English
CALCIUM PHOSPHATE, DIBASIC [HSDB]
Common Name English
DICALCIUM ORTHOPHOSPHATE
Systematic Name English
PHOSPHORUS (AS DICALCIUM PHOSPHATE)
VANDF  
Common Name English
DIBASIC CALCIUM PHOSPHATE ANHYDROUS
Common Name English
Calcium phosphate dibasic [WHO-DD]
Common Name English
CALCIUM PHOSPHATE, DIBASIC [MI]
Common Name English
CALCIUM HYDROGEN MONOPHOSPHATE
Systematic Name English
ANHYDROUS DIBASIC CALCIUM PHOSPHATE [USP MONOGRAPH]
Common Name English
DIBASIC CALCIUM PHOSPHATE
Common Name English
CALCIUM (CALCIUM PHOSPHATE (DIBASIC))
Common Name English
CALCIUM HYDROGEN PHOSPHATE [EP MONOGRAPH]
Common Name English
CALCIUM (AS PHOSPHATE,DIBASIC) [VANDF]
Common Name English
DICALCIUM PHOSPHATE [INCI]
Common Name English
INS NO.341(II)
Code English
CALCIUM HYDROGEN PHOSPHATE, ANHYDROUS [WHO-IP]
Common Name English
CALCIUM PHOSPHATE (1:1) [WHO-IP]
Common Name English
E-341(II)
Code English
ANHYDROUS DIBASIC CALCIUM PHOSPHATE [JAN]
Common Name English
CALCIUM HYDROGEN PHOSPHATE (ANHYDROUS)
Common Name English
PHOSPHORIC ACID, CALCIUM SALT (1:1)
Common Name English
CALCIUM HYDROGEN PHOSPHATE
Systematic Name English
SECONDARY CALCIUM PHOSPHATE
Common Name English
CALCIUM PHOSPHATE (1:1)
WHO-IP  
Systematic Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-341(II)
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
JECFA EVALUATION INS-341(II)
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
Code System Code Type Description
PUBCHEM
24441
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
RXCUI
47627
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
DAILYMED
L11K75P92J
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
WIKIPEDIA
DICALCIUM PHOSPHATE
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
ANHYDROUS DIBASIC CALCIUM PHOSPHATE
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY Description: A white or almost white powder; odourless. Solubility: Practically insoluble in cold water and ethanol (~750 g/l) TS; soluble in dilute acids. Category: Tablet and capsule diluent. Storage: Calcium hydrogen phosphate should be kept in a well-closed container. Labelling: The designation on the container of Calcium hydrogen phosphate should state whether it is the dihydrate or the anhydrous form. Requirement: Calcium hydrogen phosphate contains not less than 30.9% and not more than the equivalent of 31.7% of calcium, Ca, calculated with reference to the ignited substance.
JECFA MONOGRAPH
INS-341(II)
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
FDA UNII
L11K75P92J
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
DRUG BANK
DBSALT002430
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
CHEBI
32596
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
CHEBI
4496
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
NCI_THESAURUS
C77523
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
MERCK INDEX
M2964
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY Merck Index
ChEMBL
CHEMBL2107567
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
ECHA (EC/EINECS)
231-826-1
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
HSDB
992
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
EPA CompTox
DTXSID20872529
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
CONCEPT Dietary Supplement
EVMPD
SUB16368MIG
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
RXCUI
253163
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
ALTERNATIVE
EVMPD
SUB11772MIG
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
CAS
7757-93-9
Created by admin on Fri Dec 16 17:18:34 UTC 2022 , Edited by admin on Fri Dec 16 17:18:34 UTC 2022
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY
ACTIVE MOIETY