DIHYDROXYMETHYLFURATRIZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H11N5O5
Molecular Weight	293.2355
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCN(CO)C1=NC=C(\C=C\C2=CC=C(O2)[N+]([O-])=O)N=N1

InChI

InChIKey=RQWQIVXLPCFXCO-OWOJBTEDSA-N

InChI=1S/C11H11N5O5/c17-6-15(7-18)11-12-5-8(13-14-11)1-2-9-3-4-10(21-9)16(19)20/h1-5,17-18H,6-7H2/b2-1+

HIDE SMILES / InChI

Molecular Formula	C11H11N5O5
Molecular Weight	293.2355
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: http://www.inchem.org/documents/iarc/vol24/dihydroxymethylfuratrizine.html | https://www.ncbi.nlm.nih.gov/pubmed/6543340

DIHYDROXYMETHYLFURATRIZINE was formerly used in for treatment of acute gastrointestinal infections. It induced benign and malignant tumors of the forestomach and small intestine in male mice and male rats and of the esophagus in mice.

Approval Year

PubMed

Title	Date	PubMed
Induction of SOS responses in Escherichia coli by Panfuran-S, 3-di(hydroxymethyl)amino-6-(5-nitro-2-furylethenyl)-1,2,4-triazine.	1985-11	3903488
Carcinogenic effects of 3-di(hydroxymethyl)-amino-6-(5-nitro-2-furylethenyl)-1,2,4-triazine in the small intestine of Ishibashi and Wistar rats.	1984	6543340

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:42:23 GMT 2025` Edited by `admin` on `Mon Mar 31 18:42:23 GMT 2025`
Record UNII	KZY81S445V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-529313

Preferred Name

English

DIHYDROXYMETHYLFURATRIZINE

Common Name

English

PANFURAN S [IARC]

Common Name

English

3-(BIS(HYDROXYMETHYL)AMINO)-6-(2-(5-NITRO-2-FURYL)VINYL)-1,2,4-TRIAZINE

Systematic Name

English

DIHYDROXYMETHYLFURATRIZINE [IARC]

Common Name

English

PANFURAN S

Common Name

English

FURATONE-S

Common Name

English

Dihydroxymethylfuratrizine [WHO-DD]

Common Name

English

BIS(HYDROXYMETHYL)FURATRIZINE

Common Name

English

Code System Code Type Description

PUBCHEM

6414792