U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:50:47 GMT 2023
Edited
by admin
on Sat Dec 16 11:50:47 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
KXV34A41JH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INTERLEUKIN-5 RECEPTOR SUBUNIT ALPHA
Common Name English
IL-5RA
Common Name English
CD125
Common Name English
CD-125
Common Name English
Code System Code Type Description
FDA UNII
KXV34A41JH
Created by admin on Sat Dec 16 11:50:47 GMT 2023 , Edited by admin on Sat Dec 16 11:50:47 GMT 2023
PRIMARY
From To
1_114 1_135
1_162 1_176
1_249 1_296
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_15
N 1_111
N 1_196
N 1_224
Related Record Type Details
INHIBITOR -> TARGET
FLOW CYTOMETRY (MEASURING FUCOSYLATED BENRALIZUMAB TO HUMAN EOSINOPHILS)
BINDING
EC50
INHIBITOR -> TARGET
Binds to IL-5Rα and rapidly depletes levels of eosinophils and basophils through antibody-dependent cell-mediated cytotoxicity.
BINDING
Kd
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL