Umizortamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 16:05:22 GMT 2025` Edited by `admin` on `Wed Apr 02 16:05:22 GMT 2025`
Protein Type	TETRASPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	KX8KZX98PB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin, tetraspecific, anti-(human CD3 antigen ?-chain and ?-chain) (human-Oryctolagus cuniculus clone 284A10 single-chain variable fragment VL-(GGGGS)4-VH) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin G1 anti-(h

Preferred Name

English

Umizortamig

Official Name

English

scFv-G1-scFv-scFv fused heavy chain humanized and chimeric (1-1231)[scFv kappa-heavy anti-CD3E and CD3G humanized (1-252) [V-KAPPA (Homo sapiens IGKV1-5*01 (90.1%) -IGKJ4*01 (90.9%), CDR-IMGT[6.3.14] (27-32.50-52.89-102)) (1-112) -20-mer tetrakis(tetragl

Common Name

English

umizortamig [INN]

Common Name

English

immunoglobulin scFv-G1-scFv-scFv_L-kappa, anti-[Homo sapiens EGFRvIII (epidermal growth factor receptor (receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB) variant III)], anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4) and CD3G], anti-[Homo

Common Name

English

Code System Code Type Description

SMS_ID

300000056443