Umizortamig

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:29:10 UTC 2023` Edited by `admin` on `Sat Dec 16 19:29:10 UTC 2023`
Protein Type	TETRASPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	KX8KZX98PB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Umizortamig

Official Name

English

scFv-G1-scFv-scFv fused heavy chain humanized and chimeric (1-1231)[scFv kappa-heavy anti-CD3E and CD3G humanized (1-252) [V-KAPPA (Homo sapiens IGKV1-5*01 (90.1%) -IGKJ4*01 (90.9%), CDR-IMGT[6.3.14] (27-32.50-52.89-102)) (1-112) -20-mer tetrakis(tetragl

Common Name

English

umizortamig [INN]

Common Name

English

Immunoglobulin, tetraspecific, anti-(human CD3 antigen ε-chain and γ-chain) (human-Oryctolagus cuniculus clone 284A10 single-chain variable fragment VL-(GGGGS)4-VH) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin G1 anti-

Common Name

English

immunoglobulin scFv-G1-scFv-scFv_L-kappa, anti-[Homo sapiens EGFRvIII (epidermal growth factor receptor (receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB) variant III)], anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4) and CD3G], anti-[Homo

Common Name

English

Code System Code Type Description

CAS

2599198-83-9

Created by admin on Sat Dec 16 19:29:11 UTC 2023 , Edited by admin on Sat Dec 16 19:29:11 UTC 2023

PRIMARY

INN

12292

Created by admin on Sat Dec 16 19:29:11 UTC 2023 , Edited by admin on Sat Dec 16 19:29:11 UTC 2023

PRIMARY

FDA UNII

KX8KZX98PB

Created by admin on Sat Dec 16 19:29:11 UTC 2023 , Edited by admin on Sat Dec 16 19:29:11 UTC 2023

PRIMARY

From	To
1_487	2_487
1_490	2_490
2_481	4_214
1_481	3_214
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
1_1142	1_1207
2_1142	2_1207
1_1000	1_1076
2_1000	2_1076
1_882	1_947
2_882	2_947
1_739	1_815
2_739	2_815
1_628	1_686
2_628	2_686
1_522	1_582
2_522	2_582
1_405	1_461
2_405	2_461
1_284	1_358
2_284	2_358
1_154	1_227
2_154	2_227
1_23	1_88
2_23	2_88