Ipanumeran

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 20:52:33 GMT 2025` Edited by `admin` on `Wed Apr 02 20:52:33 GMT 2025`
Nucleic Acid Type	MRNA
Sequence Type	COMPLETE
Record UNII	KX68C3V7Q2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ipanumeran

Official Name

English

RNA (recombinant 5?-[1,2-[m7Gm-(5??5?)-p-[P(R)]-sp-p-G]]-capped codon-optimized human claudin CLDN6-specifying plus 5?- and 3?-untranslated flanking region-containing poly(A)-tailed messenger RBL005.4), inner salt

Preferred Name

English

messenger RNA (mRNA), 5'[1,2-[m7Gm-(5'?5')-p-[P(R)]-sp-p-G]]-capped, encoding codon-optimised human claudin-6 (CLDN6), flanked by 5' and 3' untranslated regions (UTRs), followed by a 3' polyadenylation (polyA) tail. The 5' UTR is derived from the human a

Common Name

English

ipanumeran [INN]

Common Name

English

Code System Code Type Description

FDA UNII

KX68C3V7Q2

Created by admin on Wed Apr 02 20:52:33 GMT 2025 , Edited by admin on Wed Apr 02 20:52:33 GMT 2025

PRIMARY

CAS

3026599-66-3

Created by admin on Wed Apr 02 20:52:33 GMT 2025 , Edited by admin on Wed Apr 02 20:52:33 GMT 2025

NO STRUCTURE GIVEN

INN

13541

Created by admin on Wed Apr 02 20:52:33 GMT 2025 , Edited by admin on Wed Apr 02 20:52:33 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_1145	1145 / 1145

Linkage	Site Range	Site Count
Phosphate	1_2-1_1145	1144 / 1144

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS	G		UNSPECIFIED SUBSTANCE	fd4a4c35 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
FI element	NUCLEIC ACID FEATURE
Poly A	NUCLEIC ACID FEATURE
hAg-Kozak	NUCLEIC ACID FEATURE
CLDN6	NUCLEIC ACID FEATURE