ELIVALDOGENE AUTOTEMCEL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Tue Apr 01 23:44:50 GMT 2025` Edited by `admin` on `Tue Apr 01 23:44:50 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	bone marrow
Fraction Material Type	cells
Fraction Name	hematopoietic stem cells
Record UNII	KUM75TD6SG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SKYSONA

Preferred Name

English

ELIVALDOGENE AUTOTEMCEL

Official Name

English

Elivaldogene autotemcel [WHO-DD]

Common Name

English

THE CD34+ ENRICHED CELL POPULATION CONTAINING HEMATOPOIETIC STEM AND PROGENITOR CELLS IS OBTAINED FROM AUTOLOGOUS PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) COLLECTED BY APHERESIS FROM THE PATIENT FOLLOWING MOBILIZATION OF LEUKOCYTES. THE LENTI-D LVV IS

Common Name

English

ELIVALDOGENE AUTOTEMCEL [USAN]

Common Name

English

elivaldogene autotemcel [INN]

Common Name

English

Code System Code Type Description

INN

10901

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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USAN

GH-141

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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DAILYMED

KUM75TD6SG

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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FDA UNII

KUM75TD6SG

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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NCI_THESAURUS

C171808

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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SMS_ID

300000010805

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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RXCUI

2612527

Created by admin on Tue Apr 01 23:44:50 GMT 2025 , Edited by admin on Tue Apr 01 23:44:50 GMT 2025

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Related Record Type Details


					GK3D7Z9R9V

ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1

EXPRESSED PROTEIN->VECTOR

Amount:

Related Record Type Details


					KUM75TD6SG

ELIVALDOGENE AUTOTEMCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURE	Pre-stimulation	IMMUNOLOGICAL		MUPLESTIM	A802907MI4
CULTURE	Pre-stimulation	IMMUNOLOGICAL		FLT-3 LIGAND PROTEIN (MAMMALIAN GLYCOSYLATION)	6S1KJ9KP8S
GENE TRANSDUCTION	GENE EXPRESSION	RETROVIRAL TRANSFECTION		ELIVALDOGENE TAVALENTIVEC	VI2NBA6B8C
	CD34+ Cell Enrichment	CELL SEPARATION		HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34	ZWL6BH0E0S
CULTURE	Pre-stimulation	IMMUNOLOGICAL		RECOMBINANT HUMAN THROMBOPOIETIN	E2E529W34D

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					ELIVALDOGENE TAVALENTIVEC TRANSGENE INSERT	FAO1H5M18V
VECTOR EXPRESSED PROTEIN					ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1	GK3D7Z9R9V