TIXANOX

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H10O5S
Molecular Weight	302.302
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[S+]([O-])C1=CC2=C(OC3=C(C=C(C=C3)C(O)=O)C2=O)C=C1

InChI

InChIKey=PCVFKIXSNYJABV-UHFFFAOYSA-N

InChI=1S/C15H10O5S/c1-21(19)9-3-5-13-11(7-9)14(16)10-6-8(15(17)18)2-4-12(10)20-13/h2-7H,1H3,(H,17,18)

HIDE SMILES / InChI

Molecular Formula	C15H10O5S
Molecular Weight	302.302
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6159030 | https://www.ncbi.nlm.nih.gov/pubmed/533884 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 812, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Tixanox is an antiallergic drug. It blocks histamine release from human lung induced by anti-IgE. Tixanox has been shown to be orally active against exercise-induced asthma in man.

Approval Year

PubMed

Title	Date	PubMed
Reaction of 1-O-acyl glucuronides with 4-(p-nitrobenzyl)pyridine.	1986-03-01	2870894
Synthesis and aldose reductase inhibitory activity of 7-sulfamoylxanthone-2-carboxylic acids.	1980-11	6779009
The activity of sodium cromoglycate analogues in human lung in vitro: a comparison with rat passive cutaneous anaphylaxis and clinical efficacy.	1980-10	6159030
Dibenzotropone- and dibenzosuberonecarboxylic acids with bronchodilator activity.	1979-11	533884

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:50:39 GMT 2025` Edited by `admin` on `Mon Mar 31 17:50:39 GMT 2025`
Record UNII	KQT9O2462E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TIXANOX

Official Name

English

RS-7337

Preferred Name

English

9H-XANTHENE-2-CARBOXYLIC ACID, 7-(METHYLSULFINYL)-9-OXO-

Common Name

English

7-(Methylsulfinyl)-9-oxoxanthene-2-carboxylic acid

Systematic Name

English

TIXANOX [USAN]

Common Name

English

tixanox [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712