TG-003

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H15NO2S
Molecular Weight	249.329
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1\C(SC2=CC=C(OC)C=C12)=C\C(C)=O

InChI

InChIKey=BGVLELSCIHASRV-QPEQYQDCSA-N

InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-

HIDE SMILES / InChI

Molecular Formula	C13H15NO2S
Molecular Weight	249.329
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Dual specificity protein kinase CLK4 1 Target ID: CHEMBL1075283 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15010457	Inhibitor 8504	15.0 nM [IC50]
Dual specificity protein kinase CLK1 1 Target ID: CHEMBL1075280 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15010457	Inhibitor 8504	20.0 nM [IC50]
Dual specificity protein kinase CLK2 2 Target ID: CHEMBL1075281 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15010457	Inhibitor 8504	200.0 nM [IC50]
Dual-specificity tyrosine-phosphorylation regulated kinase 1A 2 Target ID: CHEMBL4750 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25264830	Inhibitor 8504	24.0 nM [IC50]
Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1 Target ID: Q9Z188 Gene ID: 13549.0 Gene Symbol: Dyrk1b Target Organism: Mus musculus (Mouse) Sources: https://www.ncbi.nlm.nih.gov/pubmed/25264830	Inhibitor 8504	34.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 10:28:20 GMT 2025` Edited by `admin` on `Wed Apr 02 10:28:20 GMT 2025`
Record UNII	KPC5K8BPP7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TG003

Preferred Name

English

TG-003

Code

English

(Z)-1-(3-ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Systematic Name

English

(1Z)-1-(3-ETHYL-5-METHOXY-2(3H)-BENZOTHIAZOLYLIDENE)-2-PROPANONE

Systematic Name

English

2-PROPANONE, 1-(3-ETHYL-5-METHOXY-2(3H)-BENZOTHIAZOLYLIDENE)-, (1Z)-

Systematic Name

English

Code System Code Type Description

CAS

719277-26-6

Created by admin on Wed Apr 02 10:28:20 GMT 2025 , Edited by admin on Wed Apr 02 10:28:20 GMT 2025

PRIMARY

PUBCHEM

1893668

Created by admin on Wed Apr 02 10:28:20 GMT 2025 , Edited by admin on Wed Apr 02 10:28:20 GMT 2025

PRIMARY

FDA UNII

KPC5K8BPP7

Created by admin on Wed Apr 02 10:28:20 GMT 2025 , Edited by admin on Wed Apr 02 10:28:20 GMT 2025

PRIMARY

Related Record Type Details


					MDT6OZC3EE

DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2

TARGET -> INHIBITOR