Difethialone is an anticoagulant used as a rodenticide. Difethialone is not approved for use in Europe but is still used elsewhere. It is relatively volatile, has low potential to leach to groundwater but is highly persistent in soils. It is highly toxic to humans and considered to produce adverse effects on the reproduction system. In May 2008, the United States Environmental Protection Agency banned the use of difethialone in consumer-use rodenticide products and also for exterior use by commercial applicators.
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