Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H7NO4 |
| Molecular Weight | 181.1455 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CC1=CC=C(C=C1)[N+]([O-])=O
InChI
InChIKey=YBADLXQNJCMBKR-UHFFFAOYSA-N
InChI=1S/C8H7NO4/c10-8(11)5-6-1-3-7(4-2-6)9(12)13/h1-4H,5H2,(H,10,11)
| Molecular Formula | C8H7NO4 |
| Molecular Weight | 181.1455 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cured of "stickiness", poly-L β-hairpin is promoted with LL-to-DD mutation as a protein and a hydrolase mimic. | 2010-12-23 |
|
| Continuous reduction of plasma paraoxonase activity with increasing dialysis vintage in hemodialysis patients. | 2010-12 |
|
| A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies. | 2010-06-15 |
|
| Carbonic anhydrase inhibitors: Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids. | 2010-05 |
|
| Hyperthermostable acetyl xylan esterase. | 2010-01 |
|
| Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours. | 2009-08-18 |
|
| Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. | 2009-04-15 |
|
| Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin. | 2008-11-07 |
|
| CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay. | 2008-11-03 |
|
| A new lipase isolated from oleaginous seeds from Pachira aquatica (Bombacaceae). | 2008-09 |
|
| Ethyl 4-nitro-phenyl-acetate. | 2008-01-16 |
|
| Purification and some kinetic properties of carbonic anhydrase from rainbow trout (Oncorhynchus mykiss) liver and metal inhibition. | 2008 |
|
| Effects of some metals on carbonic anhydrase from brains of rainbow trout. | 2008 |
|
| Synthesis of cyclic oligomers from histidine-derived building blocks using dynamic combinatorial chemistry. | 2007-11-23 |
|
| Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver. | 2007-11 |
|
| Change in the acid hydrolysis mechanism of esters enforced by strongly acid microemulsions. | 2007-10-04 |
|
| Involvement of up-regulation of hepatic breast cancer resistance protein in decreased plasma concentration of 7-ethyl-10-hydroxycamptothecin (SN-38) by coadministration of S-1 in rats. | 2007-09 |
|
| Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction. | 2007-07 |
|
| Exploiting the yeast L-A viral capsid for the in vivo assembly of chimeric VLPs as platform in vaccine development and foreign protein expression. | 2007-05-02 |
|
| Aspirin is a substrate for paraoxonase-like activity: implications in atherosclerosis. | 2007-04 |
|
| Increased alanine concentration is associated with exposure to fenitrothion but not carbamates in Chironomus riparius larvae. | 2007-03 |
|
| Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay. | 2007-02 |
|
| Cyclodecyl 4-nitrophenylacetate. | 2006-10 |
|
| Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: structure-activity comparison of sulfamates and sulfamides. | 2006-08 |
|
| Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption. | 2005-08 |
|
| From decanoate micelles to decanoic acid/dodecylbenzenesulfonate vesicles. | 2005-07-05 |
|
| Acidic residues emulate a phosphorylation switch to enhance the activity of rat hepatic neutral cytosolic cholesterol esterase. | 2005-05-01 |
|
| Plasma and whole blood pharmacokinetics of topiramate: the role of carbonic anhydrase. | 2005-02 |
|
| Reduction of methemoglobin via electron transfer from photoreduced flavin: restoration of O2-binding of concentrated hemoglobin solution coencapsulated in phospholipid vesicles. | 2004-09-16 |
|
| Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution. | 2003-07-11 |
|
| Lack of association between serum paraoxonase 1 activities and increased oxidized low-density lipoprotein levels in impaired glucose tolerance and newly diagnosed diabetes mellitus. | 2003-04 |
|
| Biochemical detection of esterases in the adult female integument of organophosphate-resistant Boophilus microplus (Acari: Ixodidae). | 2003-01 |
|
| Mapping of the active site of rat kidney gamma-glutamyl transpeptidase using activated esters and their amide derivatives. | 2002-12 |
|
| Secreted and tumour targeted human carboxylesterase for activation of irinotecan. | 2002-09-09 |
|
| Studies on the catalytic behaviour of a cholinesterase-like abzyme in an AOT microemulsion system. | 2002-08-07 |
|
| Reactions of oximate alpha-nucleophiles with esters: evidence from solvation effects for substantial decoupling of desolvation and bond formation. | 2002-07-31 |
|
| [Synthesis and fluorescence property of complexes of rare-earth with p-nitrophenylacetic acid]. | 2002-06 |
|
| Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expression. | 2002-05 |
|
| Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. | 2002-04 |
|
| Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties. | 2002-01-17 |
|
| The stability of methacrylate biomaterials when enzyme challenged: kinetic and systematic evaluations. | 2001-12-15 |
|
| Regulation of rat carboxylesterase expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): a dose-dependent decrease in mRNA levels but a biphasic change in protein levels and activity. | 2001-11 |
|
| [Synthesis, characterization and fluorescence property of europium ternary complex p-nitrophenylacetic acid and 1, 10-phenanthroline]. | 2001-10 |
|
| Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase. | 2001-08-31 |
|
| Synthesis, molecular modeling, and structure-activity relationship of benzophenone-based CAAX-peptidomimetic farnesyltransferase inhibitors. | 2001-08-30 |
|
| On the occurrence of multiple isoprenylated cysteine methyl ester hydrolase activities in bovine adrenal medulla. | 2001-06-01 |
|
| Biochemical mechanisms of resistance in strains of Oryzaephilus surinamensis (Coleoptera: Silvanidae) resistant to malathion and chlorpyrifos-methyl. | 2001-06 |
|
| Carbonic anhydrase from bovine bone. | 2001-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:24:15 GMT 2025
by
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on
Mon Mar 31 19:24:15 GMT 2025
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| Record UNII |
KLB4P626RE
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| Record Status |
Validated (UNII)
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