Cebsulfase alfa

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 15:03:12 GMT 2025` Edited by `admin` on `Wed Apr 02 15:03:12 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	SULFATASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	KK93B9NF24
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METAZYM

Preferred Name

English

Cebsulfase alfa

Official Name

English

HGT-1110

Code

English

Cerebroside sulfatase [51-formylglycine] (recombinant human)

Common Name

English

SHP-611

Code

English

RECOMBINANT HUMAN ARYLSULFATASE A

Common Name

English

cebsulfase alfa [INN]

Common Name

English

TAK-611

Common Name

English

Cebsulfase alfa (human cerebroside-sulfatase (cerebroside-3-sulfate 3-sulfohydrolase, arylsulfatase A, ARSA, ASA, EC:3.1.6.8), produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa)

Common Name

English

Recombinant human sulfatidate sulfatase

Common Name

English

CEBSULFASE ALFA [USAN]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/03/158

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

FDA ORPHAN DRUG

170903

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

FDA ORPHAN DRUG

254207

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

Code System Code Type Description

CAS

2640112-07-6

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

USAN

KL-106

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

SMS_ID

300000008720

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

INN

12404

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

FDA UNII

KK93B9NF24

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

NCI_THESAURUS

C190463

Created by admin on Wed Apr 02 15:03:12 GMT 2025 , Edited by admin on Wed Apr 02 15:03:12 GMT 2025

PRIMARY

From	To
1_475	1_481
1_471	1_484
1_470	1_482
1_282	1_396
1_143	1_150
1_138	1_154

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_140
N	1_166
N	1_332

Related Record Type Details


					EJS32ZO2L4

ARYLSULFATASE A

TARGET->ENZYME REPLACEMENT

Amount:

Related Record Type Details


					KK93B9NF24

Cebsulfase alfa

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_51]			Amount:	3-OXO-ALANINE	3LXS1M9IE5

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL