ACRIXOLIMAB

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:17:38 GMT 2023` Edited by `admin` on `Sat Dec 16 18:17:38 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	KHG83J8RMW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ACRIXOLIMAB

Official Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA4 HEAVY CHAIN HOMO SAPIENS (1-441) (VH (HOMO SAPIENS IGHV3-30*01 (95.8%)-(IGHD)- IGHJ5*01 (100%), CDR-IMGT (8.8.7) (26-

Common Name

English

acrixolimab [INN]

Common Name

English

IMMUNOGLOBULIN G4 (222-PROLINE), ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN MONOCLONAL YBL-006 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL YBL-006 .KAPPA.-CHAIN, DIMER

Common Name

English

Code System Code Type Description

CAS

2506324-29-2

Created by admin on Sat Dec 16 18:17:38 GMT 2023 , Edited by admin on Sat Dec 16 18:17:38 GMT 2023

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FDA UNII

KHG83J8RMW

Created by admin on Sat Dec 16 18:17:38 GMT 2023 , Edited by admin on Sat Dec 16 18:17:38 GMT 2023

PRIMARY

INN

11969

Created by admin on Sat Dec 16 18:17:38 GMT 2023 , Edited by admin on Sat Dec 16 18:17:38 GMT 2023

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NCI_THESAURUS

C188591

Created by admin on Sat Dec 16 18:17:38 GMT 2023 , Edited by admin on Sat Dec 16 18:17:38 GMT 2023

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From	To
1_22	1_96
2_22	2_96
2_128	4_220
2_141	2_197
2_255	2_315
1_128	3_220
2_361	2_419
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_141	1_197
1_220	2_220
1_223	2_223
1_255	1_315
1_361	1_419

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_291
N	2_291

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL