U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12H9ClF3N3O
Molecular Weight 303.668
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORFLURAZON

SMILES

CNC1=C(Cl)C(=O)N(N=C1)C2=CC=CC(=C2)C(F)(F)F

InChI

InChIKey=NVGOPFQZYCNLDU-UHFFFAOYSA-N
InChI=1S/C12H9ClF3N3O/c1-17-9-6-18-19(11(20)10(9)13)8-4-2-3-7(5-8)12(14,15)16/h2-6,17H,1H3

HIDE SMILES / InChI

Molecular Formula C12H9ClF3N3O
Molecular Weight 303.668
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Carotenoid inhibitors reduce strigolactone production and Striga hermonthica infection in rice.
2010-12-01
PDS activity acts as a rheostat of retrograde signaling during early chloroplast biogenesis.
2010-12
Multiple stressor effects of high light irradiance and photosynthetic herbicides on growth and survival of the green alga Chlamydomonas reinhardtii.
2010-10
Screening and selection of high carotenoid producing in vitro tomato cell culture lines for [13C]-carotenoid production.
2010-09-22
The Arabidopsis plastid-signalling mutant gun1 (genomes uncoupled1) shows altered sensitivity to sucrose and abscisic acid and alterations in early seedling development.
2010-08
Rop GTPase and its target Cdc42/Rac-interactive-binding motif-containing protein genes respond to desiccation during pollen maturation.
2010-07
One amino acid substitution in phytoene desaturase makes Chlorella zofingiensis resistant to norflurazon and enhances the biosynthesis of astaxanthin.
2010-06
Editing of accD and ndhF chloroplast transcripts is partially affected in the Arabidopsis vanilla cream1 mutant.
2010-06
Transcriptional regulation of the CRK/DUF26 group of receptor-like protein kinases by ozone and plant hormones in Arabidopsis.
2010-05-25
The surface charge density of plant cell membranes (sigma): an attempt to resolve conflicting values for intrinsic sigma.
2010-05
Designer amphiphilic short peptides enhance thermal stability of isolated photosystem-I.
2010-04-21
Chlorophyll-deficient mutants of Chlamydomonas reinhardtii that accumulate magnesium protoporphyrin IX.
2010-04
In-depth analysis of the distinctive effects of norflurazon implies that tetrapyrrole biosynthesis, organellar gene expression and ABA cooperate in the GUN-type of plastid signalling.
2010-04
A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus.
2010-03
Chloroplast and reactive oxygen species involvement in apoptotic-like programmed cell death in Arabidopsis suspension cultures.
2010
Evidence that norflurazon affects chloroplast lipid unsaturation in soybean leaves (Glycine max L.).
2009-12-09
Crosstalks between myo-inositol metabolism, programmed cell death and basal immunity in Arabidopsis.
2009-10-08
The making of a chloroplast.
2009-10-07
Physiological modes of action of fluoxetine and its human metabolites in algae.
2009-09-01
Lemna minor L. as a model organism for ecotoxicological studies performing 1H NMR fingerprinting.
2009-08
Comparative ecophysiology of the xanthophyll cycle in six marine phytoplanktonic species.
2009-08
Herbicide treatments alter carotenoid profiles for 14C tracer production from tomato ( Solanum lycopersicum cv. VFNT cherry) cell cultures.
2009-06-10
Arabidopsis CHLI2 can substitute for CHLI1.
2009-06
Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum.
2009-04-10
ABA inhibits germination but not dormancy release in mature imbibed seeds of Lolium rigidum Gaud.
2009
Effects of norflurazon on green and brown hydra.
2009
QSAR analysis and specific endpoints for classifying the physiological modes of action of biocides in synchronous green algae.
2008-10-20
Investigation of norflurazon pesticide photodegradation using plasma desorption time-of-flight mass spectrometry analysis.
2008-08
Regulation of salt and ABA responses by CIPK14, a calcium sensor interacting protein kinase in Arabidopsis.
2008-05
Aquatic risk assessment of herbicides in freshwater ecosystems of South Florida.
2008-05
Co-regulation of nuclear genes encoding plastid ribosomal proteins by light and plastid signals during seedling development in tobacco and Arabidopsis.
2008-03
Abscisic acid, high-light, and oxidative stress down-regulate a photosynthetic gene via a promoter motif not involved in phytochrome-mediated transcriptional regulation.
2008-01
Is gene activity in plant cells affected by UMTS-irradiation? A whole genome approach.
2008
An Arabidopsis mutant able to green after extended dark periods shows decreased transcripts of seed protein genes and altered sensitivity to abscisic acid.
2008
Effect of various cyclodextrins on photodegradation of a hydrophobic herbicide in aqueous suspensions of different soil colloidal components.
2007-09
Effect of norflurazon on resorcinolic lipid metabolism in rye seedlings.
2007-06-05
Norflurazon mobility, dissipation, activity, and persistence in a sandy soil as influenced by formulation.
2007-05-02
Norflurazon and simazine losses in surface runoff water from flatwoods citrus production areas.
2007-05
Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling.
2007-05
Time-dependent sorption of norflurazon in four different soils: use of beta-cyclodextrin solutions for remediation of pesticide-contaminated soils.
2007-04-02
New observations on green hydra symbiosis.
2007
Herbicide resistance of transgenic rice plants expressing human CYP1A1.
2006-08-21
[Tetrapyrrole involvement in expression regulation of a nuclear gene of low-molecular-weight plastid protein ELIP].
2006-08-02
Guard cells in albino leaf patches do not respond to photosynthetically active radiation, but are sensitive to blue light, CO2 and abscisic acid.
2006-08
Effect of the simultaneous addition of beta-cyclodextrin and the herbicide norflurazon on its adsorption and movement in soils.
2006-06-28
Metabolic engineering of potato tuber carotenoids through tuber-specific silencing of lycopene epsilon cyclase.
2006-06-26
beta-Carotene accumulation induced by the cauliflower Or gene is not due to an increased capacity of biosynthesis.
2006-06
Toxicity of the norflurazon to the aquatic macrophyte Vallisneria americana (Michx.).
2006-06
Phytoremediation of the herbicides atrazine and metolachlor by transgenic rice plants expressing human CYP1A1, CYP2B6, and CYP2C19.
2006-04-19
Characterization of a higher plant herbicide-resistant phytoene desaturase and its use as a selectable marker.
2006-03
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 18:53:07 GMT 2025
Edited
by admin
on Mon Mar 31 18:53:07 GMT 2025
Record UNII
KES1HB07E4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORFLURAZON
HSDB   ISO   MI  
Common Name English
EVITAL
Preferred Name English
1-(3-TRIFLUOROMETHYLPHENYL)-4-METHYLAMINO-5-CHLOROPYRIDAZONE
Systematic Name English
TELOK
Brand Name English
SAN 9789
Code English
NORFLURAZON [HSDB]
Common Name English
NORFLURAZON [MI]
Common Name English
SAN-9789
Code English
PREDICT
Brand Name English
ZORIAL
Brand Name English
SOLICAM
Brand Name English
NORFLURAZON [ISO]
Common Name English
4-CHLORO-5-(METHYLAMINO)-2-(3-(TRIFLUOROMETHYL)PHENYL)-3(2H)-PYRIDAZINONE
Systematic Name English
4-CHLORO-5-METHYLAMINO-2-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)PYRIDAZIN-3(2H)-ONE
Systematic Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 105801
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
Code System Code Type Description
EPA CompTox
DTXSID8024234
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
ECHA (EC/EINECS)
248-397-1
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
CAS
27314-13-2
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
CHEBI
50842
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
MERCK INDEX
m8060
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY Merck Index
FDA UNII
KES1HB07E4
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
ALANWOOD
norflurazon
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
HSDB
6845
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY
PUBCHEM
33775
Created by admin on Mon Mar 31 18:53:07 GMT 2025 , Edited by admin on Mon Mar 31 18:53:07 GMT 2025
PRIMARY