Linoserpaturev

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 20:56:39 GMT 2025` Edited by `admin` on `Wed Apr 02 20:56:39 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family	Herpesviridae
Organism Genus	Simplexvirus
Organism Species	human herpesvirus 1
Author	NONE
Infraspecific Type	STRAIN
Infraspecific Name	HSV-1 F/partially del 34.5/add truncated 34.5
Part	whole
Record UNII	KCT7UM8G55
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Linoserpaturev

Official Name

English

DNA (recombinant tumor-selective replicating oncolytic human alphaherpesvirus 1 strain F vector CAN-3110 viral protein ICP34.5 gene deletion plus truncated ribonucleoside diphosphate reductase large subunit gene UL39-containing plus Rattus norvegicus nes

Preferred Name

English

linoserpaturev [INN]

Common Name

English

recombinant oncolytic herpes simplex virus type 1 (HSV-1) F strain in which both copies of the viral gamma 1 34.5 gene (?134.5, infected cell protein 34.5 [ICP34.5]) plus the ribonucleoside-diphosphate reductase large subunit UL39 (ICP6 gene) locus have

Common Name

English

Code System Code Type Description

FDA UNII

KCT7UM8G55