CX-046684

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 19:09:44 GMT 2025` Edited by `admin` on `Wed Apr 02 19:09:44 GMT 2025`
Nucleic Acid Type	mRNA VACCINE
Sequence Origin	VIRAL
Sequence Type	COMPLETE
Record UNII	KCK3ADW2DH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CX-046684

Code

English

RNA (recombinant 5?-(m7G-(5??5?)-ppp-Gm)-capped all uridine?N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 pre-fusion spike glycoprotein [982-proline,983-proline] KP.2 variant plus 5?- and 3?-untranslated flanking regi

Preferred Name

English

Code System Code Type Description

CAS

3040055-31-7

Created by admin on Wed Apr 02 19:09:44 GMT 2025 , Edited by admin on Wed Apr 02 19:09:44 GMT 2025

PRIMARY

FDA UNII

KCK3ADW2DH

Created by admin on Wed Apr 02 19:09:44 GMT 2025 , Edited by admin on Wed Apr 02 19:09:44 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_4092	4092 / 4092

Linkage	Site Range	Site Count
Phosphate	1_2-1_4092	4091 / 4091

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION		SITE_SPECIFIC	U		N1-METHYLPSEUDOURIDINE	09RAD4M6WF
BASE REPLACEMENT (NON-CODING)	[1_1]	5'-TERMINUS	G		5'-GUANOSINE-M-RNA-CAP-1-3'-PHOSPHATE	T0HQY09X7B

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ORF	NUCLEIC ACID FEATURE
PolyA tail + XbaI scar	NUCLEIC ACID FEATURE
5? UTR	NUCLEIC ACID FEATURE
3? UTR	NUCLEIC ACID FEATURE