Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H30N2O2 |
| Molecular Weight | 342.4751 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(CC[C@@](C)(N)CO)=CC=C1C(=O)CCCC2=CC=C(C)C=C2
InChI
InChIKey=YXEQXPNSBUIRDZ-OAQYLSRUSA-N
InChI=1S/C21H30N2O2/c1-16-7-9-17(10-8-16)5-4-6-20(25)19-12-11-18(23(19)3)13-14-21(2,22)15-24/h7-12,24H,4-6,13-15,22H2,1-3H3/t21-/m1/s1
| Molecular Formula | C21H30N2O2 |
| Molecular Weight | 342.4751 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
CS-0777 is a selective and orally active agonist of S1P receptor-1, discovered by Daiichi Sankyo Co., Ltd. Oral administration of CS-0777 to rats led to a significant decrease in lymphocyte count. The drug was investigated in phase 1 clinical trial in multiple sclerosis patients. In 2014, the development of the drug was discontinued.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:55:53 GMT 2023
by
admin
on
Fri Dec 15 15:55:53 GMT 2023
|
| Record UNII |
KCH74QG79A
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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11371290
Created by
admin on Fri Dec 15 15:55:53 GMT 2023 , Edited by admin on Fri Dec 15 15:55:53 GMT 2023
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827344-05-8
Created by
admin on Fri Dec 15 15:55:53 GMT 2023 , Edited by admin on Fri Dec 15 15:55:53 GMT 2023
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KCH74QG79A
Created by
admin on Fri Dec 15 15:55:53 GMT 2023 , Edited by admin on Fri Dec 15 15:55:53 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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METABOLITE ACTIVE -> PRODRUG |
