U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:43:43 GMT 2023
Edited
by admin
on Sat Dec 16 14:43:43 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
K96EGJ218N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Volrustomig
INN   USAN  
Official Name English
MEDI5752
Code English
IMMUNOGLOBULIN G1 (134-CYSTEINE,228-VALINE,242-PHENYLALANINE,243-GLUTAMIC ACID,339-SERINE,362-CYSTEINE,374-TRYPTOPHAN), ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4) (HUMAN MONOCLONAL MEDI5752 .GAMMA.1-CHAIN), DISULFIDE WITH (122-CYSTEINE,212-
Common Name English
volrustomig [INN]
Common Name English
MEDI-5752
Code English
VOLRUSTOMIG [USAN]
Common Name English
MEDI 5752 [WHO-DD]
Common Name English
Code System Code Type Description
FDA UNII
K96EGJ218N
Created by admin on Sat Dec 16 14:43:44 GMT 2023 , Edited by admin on Sat Dec 16 14:43:44 GMT 2023
PRIMARY
INN
12168
Created by admin on Sat Dec 16 14:43:44 GMT 2023 , Edited by admin on Sat Dec 16 14:43:44 GMT 2023
PRIMARY
NCI_THESAURUS
C171937
Created by admin on Sat Dec 16 14:43:44 GMT 2023 , Edited by admin on Sat Dec 16 14:43:44 GMT 2023
PRIMARY
CAS
2407760-40-9
Created by admin on Sat Dec 16 14:43:44 GMT 2023 , Edited by admin on Sat Dec 16 14:43:44 GMT 2023
PRIMARY
USAN
JK-67
Created by admin on Sat Dec 16 14:43:44 GMT 2023 , Edited by admin on Sat Dec 16 14:43:44 GMT 2023
PRIMARY
From To
1_22 1_96
1_134 4_122
1_152 1_208
1_234 2_231
1_237 2_234
1_269 1_329
1_362 2_354
1_375 1_433
2_22 2_96
2_149 2_205
2_225 3_219
2_266 2_326
2_372 2_430
3_23 3_93
3_139 3_199
4_23 4_88
4_135 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_305
N 2_302
Related Record Type Details
TARGET -> INHIBITOR
Attenuate the inhibitory signals of CTLA-4 and PD-1 on T cells.
TARGET -> INHIBITOR
AttenuateA the inhibitory signals of CTLA-4 and PD-1. on T cells.
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL