.BETA.-K-STROPHANTHIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C36H54O14
Molecular Weight	710.8056
Optical Activity	UNSPECIFIED
Defined Stereocenters	17 / 17
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(C[C@H](OC)[C@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](C)O1)O[C@H]3CC[C@]4(C=O)[C@@]5([H])CC[C@]6(C)[C@H](CC[C@]6(O)[C@]5([H])CC[C@]4(O)C3)C7=CC(=O)OC7

InChI

InChIKey=FHIREUBIEIPPMC-SADZTDHOSA-N

InChI=1S/C36H54O14/c1-18-31(50-32-30(42)29(41)28(40)25(15-37)49-32)24(45-3)13-27(47-18)48-20-4-9-34(17-38)22-5-8-33(2)21(19-12-26(39)46-16-19)7-11-36(33,44)23(22)6-10-35(34,43)14-20/h12,17-18,20-25,27-32,37,40-44H,4-11,13-16H2,1-3H3/t18-,20+,21-,22+,23-,24+,25-,27+,28-,29+,30-,31-,32+,33-,34+,35+,36+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C36H54O14
Molecular Weight	710.8056
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	17 / 17
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/689157

β-k-Strophanthin belongs to the class of K-Strophantidin compounds which are found in species of the genus Strophanthus. It is the aglycone of k-strophanthin, an analog of ouabain. k-strophanthin is found in the ripe seeds of Strophanthus kombé and in the lily Convallaria. Pharmacological information related usage of k-Strophanthin-β in human organism is limited.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[Effect of K-strophanthin beta and olitoriside on the content of glycogen and macroergic phosphorus compounds in the myocardium in experimental myocarditis].	1972 Jan	5011191
[Study of certain species of Indian hemp as sources of K-strophanthin-beta and cymarine].	1975 Jul-Aug	130260
[Study of processes of K-strophanthin-beta complex formation with calcium ions and the effect of these processes on the cardiotonic effect of cardiac glycosides].	1978 Jul-Sep	689157
The small molecule calactin induces DNA damage and apoptosis in human leukemia cells.	2012 Sep	22828439

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:09:36 GMT 2023` Edited by `admin` on `Sat Dec 16 10:09:36 GMT 2023`
Record UNII	K935S3T1OE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

.BETA.-K-STROPHANTHIN

Common Name

English

NSC-7670

Code

English

NSC-4320

Code

English

CARD-20(22)-ENOLIDE, 3-((2,6-DIDEOXY-4-O-.BETA.-D-GLUCOPYRANOSYL-3-O-METHYL-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-5,14-DIHYDROXY-19-OXO-, (3.BETA.,5.BETA.)-

Systematic Name

English

K-STROPHANTHIN-.BETA.

Common Name

English

Code System Code Type Description

PUBCHEM

20055294