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Details

Stereochemistry ABSOLUTE
Molecular Formula C36H54O14
Molecular Weight 710.8056
Optical Activity UNSPECIFIED
Defined Stereocenters 17 / 17
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of .BETA.-K-STROPHANTHIN

SMILES

[H][C@@]1(C[C@H](OC)[C@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](C)O1)O[C@H]3CC[C@]4(C=O)[C@@]5([H])CC[C@]6(C)[C@H](CC[C@]6(O)[C@]5([H])CC[C@]4(O)C3)C7=CC(=O)OC7

InChI

InChIKey=FHIREUBIEIPPMC-SADZTDHOSA-N
InChI=1S/C36H54O14/c1-18-31(50-32-30(42)29(41)28(40)25(15-37)49-32)24(45-3)13-27(47-18)48-20-4-9-34(17-38)22-5-8-33(2)21(19-12-26(39)46-16-19)7-11-36(33,44)23(22)6-10-35(34,43)14-20/h12,17-18,20-25,27-32,37,40-44H,4-11,13-16H2,1-3H3/t18-,20+,21-,22+,23-,24+,25-,27+,28-,29+,30-,31-,32+,33-,34+,35+,36+/m1/s1

HIDE SMILES / InChI

Molecular Formula C36H54O14
Molecular Weight 710.8056
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 17 / 17
E/Z Centers 0
Optical Activity UNSPECIFIED

β-k-Strophanthin belongs to the class of K-Strophantidin compounds which are found in species of the genus Strophanthus. It is the aglycone of k-strophanthin, an analog of ouabain. k-strophanthin is found in the ripe seeds of Strophanthus kombé and in the lily Convallaria. Pharmacological information related usage of k-Strophanthin-β in human organism is limited.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
[Effect of K-strophanthin beta and olitoriside on the content of glycogen and macroergic phosphorus compounds in the myocardium in experimental myocarditis].
1972 Jan
[Study of certain species of Indian hemp as sources of K-strophanthin-beta and cymarine].
1975 Jul-Aug
[Study of processes of K-strophanthin-beta complex formation with calcium ions and the effect of these processes on the cardiotonic effect of cardiac glycosides].
1978 Jul-Sep
The small molecule calactin induces DNA damage and apoptosis in human leukemia cells.
2012 Sep

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:09:36 GMT 2023
Edited
by admin
on Sat Dec 16 10:09:36 GMT 2023
Record UNII
K935S3T1OE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
.BETA.-K-STROPHANTHIN
Common Name English
NSC-7670
Code English
NSC-4320
Code English
CARD-20(22)-ENOLIDE, 3-((2,6-DIDEOXY-4-O-.BETA.-D-GLUCOPYRANOSYL-3-O-METHYL-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-5,14-DIHYDROXY-19-OXO-, (3.BETA.,5.BETA.)-
Systematic Name English
K-STROPHANTHIN-.BETA.
Common Name English
Code System Code Type Description
PUBCHEM
20055294
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
FDA UNII
K935S3T1OE
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
CAS
560-53-2
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
NSC
4320
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
NSC
7670
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
EPA CompTox
DTXSID00971387
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY
ECHA (EC/EINECS)
209-210-9
Created by admin on Sat Dec 16 10:09:36 GMT 2023 , Edited by admin on Sat Dec 16 10:09:36 GMT 2023
PRIMARY