.BETA.-K-STROPHANTHIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C36H54O14
Molecular Weight	710.8056
Optical Activity	UNSPECIFIED
Defined Stereocenters	17 / 17
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO[C@H]1C[C@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O

InChI

InChIKey=FHIREUBIEIPPMC-SADZTDHOSA-N

InChI=1S/C36H54O14/c1-18-31(50-32-30(42)29(41)28(40)25(15-37)49-32)24(45-3)13-27(47-18)48-20-4-9-34(17-38)22-5-8-33(2)21(19-12-26(39)46-16-19)7-11-36(33,44)23(22)6-10-35(34,43)14-20/h12,17-18,20-25,27-32,37,40-44H,4-11,13-16H2,1-3H3/t18-,20+,21-,22+,23-,24+,25-,27+,28-,29+,30-,31-,32+,33-,34+,35+,36+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C36H54O14
Molecular Weight	710.8056
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	17 / 17
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/689157

β-k-Strophanthin belongs to the class of K-Strophantidin compounds which are found in species of the genus Strophanthus. It is the aglycone of k-strophanthin, an analog of ouabain. k-strophanthin is found in the ripe seeds of Strophanthus kombé and in the lily Convallaria. Pharmacological information related usage of k-Strophanthin-β in human organism is limited.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
The small molecule calactin induces DNA damage and apoptosis in human leukemia cells.	2012-09	22828439
[Study of processes of K-strophanthin-beta complex formation with calcium ions and the effect of these processes on the cardiotonic effect of cardiac glycosides].	1978-07-01	689157
[Study of certain species of Indian hemp as sources of K-strophanthin-beta and cymarine].	1975-07-01	130260
[Effect of K-strophanthin beta and olitoriside on the content of glycogen and macroergic phosphorus compounds in the myocardium in experimental myocarditis].	1972-01	5011191

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:05:17 GMT 2025` Edited by `admin` on `Mon Mar 31 23:05:17 GMT 2025`
Record UNII	K935S3T1OE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-4320

Preferred Name

English

.BETA.-K-STROPHANTHIN

Common Name

English

NSC-7670

Code

English

CARD-20(22)-ENOLIDE, 3-((2,6-DIDEOXY-4-O-.BETA.-D-GLUCOPYRANOSYL-3-O-METHYL-.BETA.-D-RIBO-HEXOPYRANOSYL)OXY)-5,14-DIHYDROXY-19-OXO-, (3.BETA.,5.BETA.)-

Systematic Name

English

K-STROPHANTHIN-.BETA.

Common Name

English

Code System Code Type Description

PUBCHEM

20055294