U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 21:12:58 GMT 2025
Edited
by admin
on Tue Apr 01 21:12:58 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
K8A4DG9RWV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Gruticibart
USAN   INN  
Official Name English
AB-023
Preferred Name English
gruticibart [INN]
Common Name English
AB023
Code English
Immunoglobulin G4 [224-proline], anti-(human blood-coagulation factor XI) (human-Mus musculus monoclonal AB023 ?-4 chain), disulfide with human-Mus musculus monoclonal AB023 ?-chain, dimer
Common Name English
GRUTICIBART [USAN]
Common Name English
Code System Code Type Description
USAN
KL-89
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
NCI_THESAURUS
C171173
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
INN
12624
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
FDA UNII
K8A4DG9RWV
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
CAS
2704554-77-6
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
SMS_ID
300000051886
Created by admin on Tue Apr 01 21:12:58 GMT 2025 , Edited by admin on Tue Apr 01 21:12:58 GMT 2025
PRIMARY
From To
1_22 1_95
1_130 3_214
1_143 1_199
1_222 2_222
1_225 2_225
1_257 1_317
1_363 1_421
2_22 2_95
2_130 4_214
2_143 2_199
2_257 2_317
2_363 2_421
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
COAGULATION FACTOR XIA
TARGET -> INHIBITOR
COAGULATION FACTOR XI
TARGET -> INHIBITOR
Kd
Related Record Type Details
Gruticibart
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966