U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:44:14 GMT 2023
Edited
by admin
on Sat Dec 16 13:44:14 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
K8A4DG9RWV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Gruticibart
USAN   INN  
Official Name English
gruticibart [INN]
Common Name English
AB023
Code English
Immunoglobulin G4 [224-proline], anti-(human blood-coagulation factor XI) (human-Mus musculus monoclonal AB023 γ-4 chain), disulfide with human-Mus musculus monoclonal AB023 κ-chain, dimer
Common Name English
AB-023
Code English
GRUTICIBART [USAN]
Common Name English
Code System Code Type Description
USAN
KL-89
Created by admin on Sat Dec 16 13:44:14 GMT 2023 , Edited by admin on Sat Dec 16 13:44:14 GMT 2023
PRIMARY
INN
12624
Created by admin on Sat Dec 16 13:44:14 GMT 2023 , Edited by admin on Sat Dec 16 13:44:14 GMT 2023
PRIMARY
FDA UNII
K8A4DG9RWV
Created by admin on Sat Dec 16 13:44:14 GMT 2023 , Edited by admin on Sat Dec 16 13:44:14 GMT 2023
PRIMARY
CAS
2704554-77-6
Created by admin on Sat Dec 16 13:44:14 GMT 2023 , Edited by admin on Sat Dec 16 13:44:14 GMT 2023
PRIMARY
From To
1_22 1_95
1_130 3_214
1_143 1_199
1_222 2_222
1_225 2_225
1_257 1_317
1_363 1_421
2_22 2_95
2_130 4_214
2_143 2_199
2_257 2_317
2_363 2_421
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
Kd
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL