U.S. Department of Health & Human Services
National Institutes of Health
NCATS
This repository is under review for potential modification in compliance with Administration directives.
Dismiss
Return Home
Inxight
Drugs
Search Substances
Home
Browse Drugs
US Approved Drugs
Marketed Drugs
Investigational Drugs
All Substances
Search
Structure Search
Sequence Search
Downloads
About
Search Substances
Avacincaptad Pegol Sodium
K86ENL12I5
US Approved Rx (2023)
First approved in 2023
General
Record Details
Names
7
Classification
1
Identifiers
6
Subunits
1
Sugars
4
Linkages
1
Relationships
1
Active Moiety
1
Modifications
2
Characteristic Attributes
1
Avacincaptad Pegol Sodium
K86ENL12I5
US Approved Rx (2023)
First approved in 2023
General
Approval Year
2023
446
Record Details
Substance Class
Nucleic Acid
Sequence Type
COMPLETE
Record UNII
K86ENL12I5
Record Status
Validated (UNII)
Record Version
17
16
15
14
13
12
11
10
9
8
7
6
5
4
3
2
1
Names
7
Show
5
20
100
All
entries
Name
Type
Language
Name
Type
Language
Avacincaptad Pegol Sodium
Official Name
English
ARC-1905
Preferred Name
English
Avacincaptad pegol sodium [WHO-DD]
Common Name
English
Poly(oxy-1,2-ethanediyl), ?-hydro-?-methoxy-, 5?-ether with RNA ((2?-deoxy-2?-fluoro)C-Gm-(2?-deoxy-2?-fluoro)C-(2?-deoxy-2?-fluoro)C-G-(2?-deoxy-2?-fluoro)C-Gm-Gm-(2?-deoxy-2?-fluoro)U-(2?-deoxy-2?-fluoro)C-(2?-deoxy-2?-fluoro)U-(2?-deoxy-2?-fluoro)C-Am
Systematic Name
English
IZERVAY
Brand Name
English
Showing 1 to 5 of 7 entries
Previous
1
2
Next
Classification
1
Show
5
20
100
All
entries
Classification Tree
Code System
Code
Classification Tree
Code System
Code
Pharmacologic Substance
Pharmacologic Substance
[C1909]
Agent Affecting Organs of Special Senses
NCI_THESAURUS
C78283
Showing 1 to 1 of 1 entries
Previous
1
Next
Identifiers
6
Show
5
20
100
All
entries
Code System
Code
Type
Description
Code System
Code
Type
Description
SMS_ID
300000044568
PRIMARY
NCI_THESAURUS
C142940
PRIMARY
FDA UNII
K86ENL12I5
PRIMARY
DAILYMED
K86ENL12I5
PRIMARY
CAS
1491144-00-3
PRIMARY
Showing 1 to 5 of 6 entries
Previous
1
2
Next
Subunits
1
Subunit 0
>SUBUNIT_0
Sugars
4
Show
5
20
100
All
entries
Sugar
Site Range
Site Count
Sugar
Site Range
Site Count
Deoxyribose (DNA)
1_39
1 / 39
2'-Fluoro-Ribose
1_1;1_3-1_4;1_6;1_9-1_12;1_16;1_18-1_19;1_23-1_25;1_29-1_31;1_33-1_35;1_37
21 / 39
2'-O-Methyl-Ribose
1_2;1_7-1_8;1_13-1_15;1_20-1_22;1_26-1_28;1_36;1_38
14 / 39
L-Ribose
1_5;1_17;1_32
3 / 39
Showing 1 to 4 of 4 entries
Previous
1
Next
Linkages
1
Show
5
20
100
All
entries
Linkage
Site Range
Site Count
Linkage
Site Range
Site Count
1_2-1_39
38 / 38
Showing 1 to 1 of 1 entries
Previous
1
Next
Relationships
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
TT0V5JLG5B
Avacincaptad Pegol
PARENT -> SALT/SOLVATE
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
Active Moiety
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
K86ENL12I5
Avacincaptad Pegol Sodium
ACTIVE MOIETY
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
Modifications
2
Structural Modifications
Show
5
20
100
All
entries
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
NUCLEOTIDE SUBSTITUTION
[1_1]
5'-TERMINUS
UNSPECIFIED SUBSTANCE
f798c9a8
(not in database)
3'-3' LINKER
[1_39]
SITE_SPECIFIC
DISODIUM THYMIDINE 3'-MONOPHOSPHATE
C7GQ0OJ477
Showing 1 to 2 of 2 entries
Previous
1
Next
Characteristic Attributes
1
Show
5
20
100
All
entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER
CHEMICAL
NUMBER 53.5 kDa (average)
Showing 1 to 1 of 1 entries
Previous
1
Next
