Alisvetcel

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 20:11:09 GMT 2023` Edited by `admin` on `Sat Dec 16 20:11:09 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	MAMMAL
Source Materials Parent	`R7AD7Y06PL` EQUUS CABALLUS WHOLE
Part	BLOOD
Fraction Name	Peripheral blood mononuclear cells (PBMCs)
Record UNII	K86DZ9E8NS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Alisvetcel

Official Name

English

Equine allogeneic chondrogenic-induced mesenchymal stromal/stem cells (MSCs), isolated from peripheral blood mononuclear cells (PBMCs) collected from donor horses. The MSCs are selected for by growing the PBMCs in media containing fetal bovine serum (FBS

Common Name

English

alisvetcel [INN]

Common Name

English

Code System Code Type Description

FDA UNII

K86DZ9E8NS

Created by admin on Sat Dec 16 20:11:09 GMT 2023 , Edited by admin on Sat Dec 16 20:11:09 GMT 2023

PRIMARY

INN

12664

Created by admin on Sat Dec 16 20:11:09 GMT 2023 , Edited by admin on Sat Dec 16 20:11:09 GMT 2023

PRIMARY

Related Record Type Details


					K7Q1JQR04M

DINOPROSTONE

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:

Related Record Type Details


					K86DZ9E8NS

Alisvetcel

ACTIVE MOIETY

Comments:

Veterinary use differentiate towards chondrocytes

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Fragment Name	Fragment ID
CULTURE		DIFFERENTION	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	Mesenchymal stromal/stem cells (MSCs) selection	CELL SEPARATION	DEXAMETHASONE	7S5I7G3JQL
CULTURE	EXPANSION	BIOLOGICAL	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	DIFFERENTIATION AGENT	DIFFERENTIATION	MECASERMIN	7GR9I2683O
CULTURE	Mesenchymal stromal/stem cells (MSCs) selection	CELL SEPARATION	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	DIFFERENTIATION AGENT	DIFFERENTIATION	HUMAN TRANSFORMING GROWTH FACTOR .BETA.-1	T7D25J14LT

Name	Property Type	Referenced Substance
ANTIGEN EXPRESSED	BIOLOGICAL	`EAD36Y912K` THY-1 MEMBRANE GLYCOPROTEIN

ANTIGEN EXPRESSED	BIOLOGICAL	`CA9PO31PIJ` TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5