U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 15:31:32 GMT 2023
Edited
by admin
on Sat Dec 16 15:31:32 GMT 2023
Source Materials Class ORGANISM
Source Materials Type VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Poxviridae
Organism Genus Orthopoxvirus
Organism Species vaccinia virus
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name Thymidine Kinase (-) Vaccinia-GM-CSF JX-594
Part WHOLE
Record UNII
K82DG47I0G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEXASTIMOGENE DEVACIREPVEC
INN   WHO-DD  
USAN   INN  
Official Name English
pexastimogene devacirepvec [INN]
Common Name English
Pexastimogene devacirepvec [WHO-DD]
Common Name English
JX-594
Code English
PEXASTIMOGENE DEVACIREPVEC [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 762820
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
NCI_THESAURUS C1962
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
NCI_THESAURUS C2674
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
FDA ORPHAN DRUG 394213
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
Code System Code Type Description
DRUG BANK
DB15069
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
NCI_THESAURUS
C71533
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
USAN
YY-136
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
FDA UNII
K82DG47I0G
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
CAS
1058624-46-6
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
ChEMBL
CHEMBL3039547
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
EVMPD
SUB182308
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
INN
9607
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
WIKIPEDIA
PEXASTIMOGENE DEVACIREPVEC
Created by admin on Sat Dec 16 15:31:32 GMT 2023 , Edited by admin on Sat Dec 16 15:31:32 GMT 2023
PRIMARY
Related Record Type Details
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
VECTOR EXPRESSED PROTEIN GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR HUMAN KIJ28K7WXF
VECTOR EXPRESSED PROTEIN BETA-GALACTOSIDASE (E.COLI K12 STRAIN) 7D9YBM8FLW
TRANSGENE SITE-SPECIFIC TK-GENE COLONY STIMULATING FACTOR 2 (HOMO SAPIENS (HUMAN) ) GENE 8ZM01Z8719
TRANSGENE SITE-SPECIFIC TK-GENE BETA-GALACTOSIDASE GENE (ESCHERICHIA COLI STR. K-12 SUBSTR. MG1655 ) 7J216MA9TX
GENE DISRUPTION SITE_SPECIFIC THYMIDINE KINASE GENE, VACCINIA VIRUS RPS4SM6B9G