U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:09:18 GMT 2023
Edited
by admin
on Sat Dec 16 18:09:18 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependovirus
Organism Species adeno-associated virus
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name AAV6 with an insertion of an anti- CD70 chimeric antigen receptor (CAR) transgen
Part WHOLE
Record UNII
K6ECA8WZF8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOLAMCABTAGENE DURZIGEDLEUCEL AAV6 VECTOR
Common Name English
VOLAMCABTAGENE DURZIGEDLEUCEL AAV6 VECTOR WITH AN INSERTION OF AN ANTI-CD70 CHIMERIC ANTIGEN RECEPTOR (CAR) TRANSGENE
Common Name English
Code System Code Type Description
FDA UNII
K6ECA8WZF8
Created by admin on Sat Dec 16 18:09:18 GMT 2023 , Edited by admin on Sat Dec 16 18:09:18 GMT 2023
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR VOLAMCABTAGENE DURZIGEDLEUCEL TRANSGENE INSERT PB39U4W7CP