Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C29H46O3 |
| Molecular Weight | 442.6737 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C
InChI
InChIKey=GRAAWEGTURLYKP-MVTMSODMSA-N
InChI=1S/C29H46O3/c1-3-4-5-6-7-8-9-10-11-28(31)32-27-17-16-26-25-14-12-21-20-22(30)13-15-23(21)24(25)18-19-29(26,27)2/h20,23-27H,3-19H2,1-2H3/t23-,24+,25+,26-,27-,29-/m0/s1
| Molecular Formula | C29H46O3 |
| Molecular Weight | 442.6737 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Nandrolone undecanoate (brand names Dynabolon) is an anabolic androgenic steroid (AAS), which had been used for the treatment of the anemia of chronic renal failure for more than 25 years. Due to concerns over adverse effects, their use historically has been limited to nandrolone decanoate given to men, usually over age 50, who have intact kidneys. It binds to the androgen receptor to a greater degree than testosterone, but due to its inability to act on the muscle in ways unmediated by the receptor, has a less overall effect on muscle growth. Despite the fact that AAS are banned substances by professional sports organizations and illegal drugs by the DEA, they are used and abused extensively, especially by teenagers and young athletes or non-athletes either for cosmetic or recreational purposes. Users may even take from 10 to 100 times higher doses than the physiological one.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: P10275 Gene ID: 367.0 Gene Symbol: AR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/18809391 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Palliative | Unknown Approved UseUnknown |
PubMed
| Title | Date | PubMed |
|---|---|---|
| The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors. | 2008-11-13 |
|
| Body mass reduction markedly improves muscle performance and body composition in obese females aged 61-75 years: comparison between the effects exerted by energy-restricted diet plus moderate aerobic-strength training alone or associated with rGH or nandrolone undecanoate. | 2004-04 |
|
| Androgen therapy for anaemia of chronic renal failure. Indications in the erythropoietin era. | 1996-10 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8936631
anemia of chronic renal failure: 200 mg per week given intramuscularly, for six months
Route of Administration:
Intramuscular
| Substance Class |
Chemical
Created
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admin
on
Edited
Mon Mar 31 19:17:23 GMT 2025
by
admin
on
Mon Mar 31 19:17:23 GMT 2025
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| Record UNII |
K64MCF1I9Z
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C2360
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94193
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SUB03388MIG
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Nandrolone undecanoate
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C95974
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862-89-5
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K64MCF1I9Z
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100000085691
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DTXSID701006644
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212-729-3
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| Related Record | Type | Details | ||
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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