Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H4N2O |
| Molecular Weight | 96.0874 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1NC=NC=C1
InChI
InChIKey=DNCYBUMDUBHIJZ-UHFFFAOYSA-N
InChI=1S/C4H4N2O/c7-4-1-2-5-3-6-4/h1-3H,(H,5,6,7)
| Molecular Formula | C4H4N2O |
| Molecular Weight | 96.0874 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | 1994 Aug 17 |
|
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | 1995 Nov 9 |
|
| The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2. | 2001 Mar 12 |
|
| A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: implications for the origin of life. | 2001 May |
|
| Ab initio study of the (5R)- and (5S)-TT pyrimidine h5(6-4) pyrimidone photoproducts. Implications on the design of new biologically relevant analogues. | 2002 Dec 27 |
|
| Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin. | 2003 Apr |
|
| Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis. | 2003 Jan 2 |
|
| The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2. | 2003 Mar 24 |
|
| Ureidopyrimidinones incorporating a functionalizable p-aminophenyl electron-donating group at C-6. | 2005 Apr 1 |
|
| A theoretical study on the structure-activity relationships of metabolites of folates as antioxidants and its implications for rational design of antioxidants. | 2005 Feb 15 |
|
| Nucleotide excision repair activity varies among murine spermatogenic cell types. | 2005 Jul |
|
| Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. | 2005 Sep |
|
| Analytical and semipreparative high performance liquid chromatography separation of stereoisomers of novel 3,4-dihydropyrimidin-4(3H)-one derivatives on the immobilised amylose-based Chiralpak IA chiral stationary phase. | 2006 Jul |
|
| UV-induced generation of rare tautomers of allopurinol and 9-methylhypoxanthine -- a matrix isolation FTIR study. | 2006 Jul 20 |
|
| H2, N2, CO, and CO2 sorption properties of a series of robust sodalite-type microporous coordination polymers. | 2006 Mar 20 |
|
| How resonance assists hydrogen bonding interactions: an energy decomposition analysis. | 2007 Jan 15 |
|
| Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides. | 2007 Jul 26 |
|
| Probing the solvent-induced tautomerism of a redox-active ureidopyrimidinone. | 2007 Jun 14 |
|
| The mechanism of ureido-pyrimidinone:2,7-diamido-naphthyridine complexation and the presence of kinetically controlled pathways in multicomponent hydrogen-bonded systems. | 2008 Apr 23 |
|
| 3D-QSAR CoMFA of a series of DABO derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors. | 2008 Aug |
|
| Synthesis, structure and spectral investigation of hydrogen bonded helical chain in mixed ligand Cu(II) pyrimidone complex. | 2008 Nov 15 |
|
| Bis[μ-3-(2-hydroxy-ethyl)-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-olato-κN,O:O]bis[aquachloridocopper(II)]. | 2008 Sep 13 |
|
| Design, synthesis, and biological evaluation of potent c-Met inhibitors. | 2008 Sep 25 |
|
| Recognition and reaction mechanisms of the (6-4) photolyase as determined by using a (6-4) photoproduct analog. | 2009 |
|
| Spectroscopic analysis of the pyrimidine(6-4)pyrimidone photoproduct: insights into the (6-4) photolyase reaction. | 2009 Jan 7 |
|
| Inhibition of iNOS and COX-2 in human whole blood ex vivo and monocyte-macrophage J774 cells by a new group of aminothiopyrimidone derivatives. | 2009 Mar 1 |
|
| An iron(II) dependent formamide hydrolase catalyzes the second step in the archaeal biosynthetic pathway to riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin. | 2009 May 19 |
|
| Formation of uracil from the ultraviolet photo-irradiation of pyrimidine in pure H2O ices. | 2009 Sep |
|
| Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications. | 2010 Apr 1 |
|
| 3-Phenyl-2-(pyrrolidin-1-yl)-5,6-dihydro-8H-thio-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one. | 2010 Aug 25 |
|
| 2-Isopropyl-6-methyl-pyrimidin-4(3H)-one. | 2010 Aug 28 |
|
| A eukaryotic-acquired gene by a biotrophic phytopathogen allows prolonged survival on the host by counteracting the shut-down of plant photosynthesis. | 2010 Jan 28 |
|
| Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents. | 2010 May 15 |
|
| Titanium(IV) isopropoxide mediated synthesis of pyrimidin-4-ones. | 2010 May 21 |
|
| Comparison of the non-radiative decay mechanisms of 4-pyrimidinone and uracil: an ab initio study. | 2010 May 21 |
|
| A short synthesis of the triazolopyrimidine antibiotic essramycin. | 2010 Nov 29 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:40:48 GMT 2023
by
admin
on
Fri Dec 15 18:40:48 GMT 2023
|
| Record UNII |
K43V90OY4L
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
224-932-4
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
157911
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
K43V90OY4L
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
20695
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
4562-27-0
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
DTXSID5063524
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
1575
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY | |||
|
51953-18-5
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
ALTERNATIVE | |||
|
Pyrimidone
Created by
admin on Fri Dec 15 18:40:48 GMT 2023 , Edited by admin on Fri Dec 15 18:40:48 GMT 2023
|
PRIMARY |