U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:59:21 GMT 2023
Edited
by admin
on Sat Dec 16 14:59:21 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
K3KZN98GF5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Patecibart
INN  
Official Name English
GMA301
Code English
Immunoglobulin G4-kappa, anti-[Homo sapiens EDNRA (endothelin receptor type A, ETA, ET-A, ETA-R, ET-AR)], humanized monoclonal antibody (gamma4 heavy chain humanized (1-446) [VH (Homo sapiens IGHV2-5*09 (88.9%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [10.7.1
Common Name English
GETAGOZUMAB
Common Name English
GMA-301
Common Name English
patecibart [INN]
Common Name English
Immunoglobulin G4 [228-proline,234-alanine,235-alanine,de-447-lysine], anti-(human endothelin ETA receptor) (human-Mus musculus monoclonal GMA301 γ4-chain), disulfide with human-Mus musculus monoclonal GMA301 κ-chain, dimer
Common Name English
Code System Code Type Description
NCI_THESAURUS
C199087
Created by admin on Sat Dec 16 14:59:22 GMT 2023 , Edited by admin on Sat Dec 16 14:59:22 GMT 2023
PRIMARY
FDA UNII
K3KZN98GF5
Created by admin on Sat Dec 16 14:59:22 GMT 2023 , Edited by admin on Sat Dec 16 14:59:22 GMT 2023
PRIMARY
INN
12333
Created by admin on Sat Dec 16 14:59:22 GMT 2023 , Edited by admin on Sat Dec 16 14:59:22 GMT 2023
PRIMARY
CAS
2642374-04-5
Created by admin on Sat Dec 16 14:59:22 GMT 2023 , Edited by admin on Sat Dec 16 14:59:22 GMT 2023
PRIMARY
From To
1_22 1_97
1_134 3_214
1_147 1_203
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
2_22 2_97
2_134 4_214
2_147 2_203
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE CHEMICAL
Molecular Formula CHEMICAL