Diphenylmethane

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H12
Molecular Weight	168.2344
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=CZZYITDELCSZES-UHFFFAOYSA-N

InChI=1S/C13H12/c1-3-7-12(8-4-1)11-13-9-5-2-6-10-13/h1-10H,11H2

HIDE SMILES / InChI

Molecular Formula	C13H12
Molecular Weight	168.2344
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.	2002-04-11	11931611
Oxygen transfer reactions. 4. Reaction of high valent oxoruthenium compounds with sulfides.	2002-04-08	11925193
Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: possible relevance for wakefulness and depression.	2002-04-01	11933055
Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.	2002-03-14	11882001
Is psychosis exacerbated by modafinil?	2002-03	11879175
Pharmacotherapy of the overactive bladder and advances in drug delivery.	2002-03	11862073
Muscarinic receptor antagonist-induced lenticular opacity in rats.	2002-03	11861984
Determination of modafinil, modafinil acid and modafinil sulfone in human plasma utilizing liquid-liquid extraction and high-performance liquid chromatography.	2002-02-15	11885856
Medication update.	2002-02	11846243
Effect of modafinil at steady state on the single-dose pharmacokinetic profile of warfarin in healthy volunteers.	2002-02	11831544
On the prodrug potential of novel aldose reductase inhibitors with diphenylmethyleneaminooxycarboxylic acid structure.	2002-02	11803127
Efficacy and safety of modafinil (Provigil) for the treatment of fatigue in multiple sclerosis: a two centre phase 2 study.	2002-02	11796766
Modafinil for fatigue in multiple sclerosis.	2002-02	11796762
Reduction of daytime sleepiness in a depressive patient during adjunct treatment with modafinil.	2002-01-05	11755461
Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.	2002-01	11862356
Effect of modafinil on the pharmacokinetics of ethinyl estradiol and triazolam in healthy volunteers.	2002-01	11823757
[The drop in toxicity and the rise in the effectiveness of antineoplastic chemotherapy by correcting the activity of liver monooxygenases: from the experiment to the clinical practice].	2002	11882969
Sleepless in America.	2001-12-17	11778569
A novel, tunable manganese coordination system based on a flexible "spacer" unit: noncovalent templation effects.	2001-12-05	11724606
Cost-Effectiveness of tolterodine for patients with urge incontinence who discontinue initial therapy with oxybutynin: a Canadian perspective.	2001-12	11813937
Is tolterodine (Detrol) or oxybutynin (Ditropan) the best for treatment of urge urinary incontinence?	2001-12	11742595
Modafinil: a gift to portmanteau.	2001-11-20	11712723
Variations in extracellular monoamines in the prefrontal cortex and medial hypothalamus after modafinil administration: a microdialysis study in rats.	2001-11-16	11733706
Palladium-catalyzed asymmetric diene cyclization/hydrosilylation employing functionalized silanes and disiloxanes.	2001-11-16	11701015
The importance of residues in substrate recognition site 3 for the catalytic function of CYP2D25 (vitamin D 25-hydroxylase).	2001-11-09	11689019
Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea.	2001-11-01	11719309
The effect of tolterodine on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive containing ethinyl estradiol and levonorgestrel.	2001-11	11768839
Tolterodine: an overview.	2001-11	11760779
Tolterodine once-daily in treatment of the overactive bladder.	2001-11	11711378
Medical treatment of overactive bladder.	2001-11	11702910
Application of different RP-HPLC methods for the determination of the octanol/water partition coefficient of selected tetrachlorobenzyltoluenes.	2001-11	11695590
Reference scales for the characterization of cationic electrophiles and neutral nucleophiles.	2001-10-03	11572670
Evidence for the efficacy and safety of tolterodine in the treatment of overactive bladder.	2001-10	11825311
Engineering the CYP101 system for in vivo oxidation of unnatural substrates.	2001-10	11739899
Tolterodine: a clinical review.	2001-10	11703885
POEMS (patient-oriented evidence that matters) spark discussion.	2001-10	11674898
[Effect of phencarol on pancreatic digestive enzymes in food anaphylaxis].	2001-09-18	11558439
Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.	2001-09-03	11527726
Tolterodine reduces the number of urge incontinence episodes in patients with an overactive bladder.	2001-09	11516807
Physiologically based pharmacokinetic model for tetrachlorobenzyltoluenes in rat: comparison of in vitro and in vivo metabolic rates.	2001-09	11509740
Resonance Rayleigh scattering study of the interaction of heparin with some basic diphenyl naphthylmethane dyes.	2001-08-15	11534715
Improvement of the synthesis of diphenylmethyl 7beta-(o-hydroxy)benzylideneamino-3-hydroxymethyl-3-cephem-4-carboxylate.	2001-08	11601651
Costs and resources associated with the treatment of overactive bladder using retrospective medical care claims data.	2001-08	11517841
Successful treatment of excessive daytime sleepiness in Parkinson's disease with modafinil.	2001-07	11518012
Fatigue in multiple sclerosis.	2001-05	11898532
[Reducing of hepatotoxicity of antineoplastic chemotherapy and concomitant viral infection through control of liver metabolism: from experiment to clinical practice].	2001	11826485
Toxicology of environmental estrogens.	2001	11800169
Modafinil in fibromyalgia treatment.	2001	11748325
Antioxidant activity of 5-alkoxymethyl-6-chromanols.	2001	11523598
Safety profile of tolterodine as used in general practice in England: results of prescription-event monitoring.	2001	11522122

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:57:41 GMT 2025` Edited by `admin` on `Mon Mar 31 18:57:41 GMT 2025`
Record UNII	K3E387I0BC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIPHENYL METHANE

Preferred Name

English

Diphenylmethane

Systematic Name

English

DITAN

Common Name

English

BENZYLBENZENE

Systematic Name

English

1,1'-METHYLENEBISBENZENE

Systematic Name

English

1,1'-METHYLENEBISBENZENE [HSDB]

Common Name

English

DIPHENYLMETHANE [MI]

Common Name

English

NSC-4708

Code

English

Code System Code Type Description

CAS

101-81-5